When you ask your doctor to write a script for #Deplin [15 mg of L-methyl folate] you can try to see if your insurance will cover it. Some do, but most do not because they want to call it a Medical Food. Which in my opinion is bogus. A food would be something you could find in nature and eat it. L-methyl folate doesn't exist in nature. Green leafy vegetables have Dihydrofolate not L-methyl folate...and Folic ACID is also not found in nature and is completely a SYNTHETIC CHEMICAL made by man.
So, in reality L-methyl folate and Folic ACID are both made by man in a chemistry lab. But L-methyl folate is at least a perfect copy of what your body should be making for itself but cannot make enough because of the MTHFR enzyme's faulty function.
The prenatal vitamin #NeeVoDHA for example has both some #Folic ACID and some #L-Methyl folate ...as long as the ratio is reasonable all should be OK. But, in a person with #MTHFR #C677T and or #A1298C mutations they have an MTHFR enzyme that is slower than molasses at turning the precursor folate into L-Methyl Folate...so a lot of Folic ACID will just backup in the blood stream and beat out what little L-Methyl folate the person is able to make.
None of the "natural forms" of folate block the folate receptors on the BLOOD BRAIN BARRIER [BBB] only the man made Folic ACID can block up the receptor site and prevent L-Methyl folate from getting into the brain. Only L-methyl folate can get into the BRAIN.
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