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Q:  What is IL13?

ag5zfnJlc291cmNlLXFuYXITCxIGQW5zd2VyGICAgIC0vZQLDA 23andMe Test Question: What is IL13? Answer: #IL13 This #gene encodes an immunoregulatory cytokine produced primarily by activated #Th2 cells. This #cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, #IL3 , #IL5 , #IL4 , and #CSF2 form a cytokine gene cluster on chromosome 5q, with this #gene particularly close to IL4. [provided by RefSeq, Jul 2008] Data provided by NCBI http://www.ncbi.nlm.nih.gov/gene/3596 #inflammatory http://resqua.com/100001600189727/what-is-il13

#IL13
This #gene encodes an immunoregulatory cytokine produced primarily by activated #Th2 cells. This #cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, #IL3 , #IL5 , #IL4 , and #CSF2 form a cytokine gene cluster on chromosome 5q, with this #gene particularly close to IL4. [provided by RefSeq, Jul 2008] Data provided by NCBI http://www.ncbi.nlm.nih.gov... #inflammatory

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