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Q:  What are some recommended Laboratory tests for MTHFR ?

ag5zfnJlc291cmNlLXFuYXITCxIGQW5zd2VyGICAgICQyc8IDA MTHFR Question: What are some recommended Laboratory tests for MTHFR ? Answer: 1) Biopterin/Neopterin: For those with A1298C mutations, #BH4 (also known as tetrahydrobiopterin) levels are typically quite low. This test provides insight to how low these levels are and why. If neopterin levels are high, then I am considering the possibility of a lingering infection, inflammation or chronic immune response that is preventing #biopterin from being formed. Thus, this test provides information not only potentially low biopterin levels but also why they may be low. If a doctor simply prescribes BH4 without understanding the need to address the inflammation and chronic infections, it is band-aide treatment over a gaping wound. Learn more about the Biopterin/Neopterin test here a) http://www.healthegoods.com/neopterin-biopterin-profile-urine.html b) http://www.metametrix.com/test-menu/profiles/vitamins/neopterin-biopterin 2) Urinary #Porphyrins : http://www.healthegoods.com/porphyrins-profile-urine.html Those with MTHFR mutations typically have elevated levels of heavy metals. This test points out the potential of heavy metals without the damaging effects of provoked urinary heavy metal testing. If urinary porphyrins are elevated, then you know you must work with a physician who is very knowledgeable about heavy metal chelation. If a physician prescribes medications or supplements without addressing heavy metal toxicity at some point, effective treatment for MTHFR cannot exist. Learn more about the Urinary Porphyrins test here: http://www.metametrix.com/test-menu/profiles/toxicants-and-detoxification/porphyrins-profile 3) Urinary 40 Amino Acids: http://www.healthegoods.com/amino-acid-profile-40-plasma.html Those with MTHFR mutations have many amino acid imbalances. Not only does the Amino Acid test identify amino acids which are imbalanced, but it also informs a knowledgeable physician of other potential mutations. Yes, it is not that easy all the time. I’ve found that while working with MTHFR mutations, I do not get the results I normally see right away. Why? Because there are other mutations present which must be identified and addressed. Amino acids are the backbone of neurotransmitters. If any are low, then symptoms of #ADD / #ADHD, depression, #bipolar , autism and other symptoms are likely present. If a physician ignores knowing which amino acids are imbalanced, symptoms will linger on and the individual with MTHFR will not recover nearly as quickly. Worse yet, symptoms may worsen if a physician prescribes a medication or supplement which aggravates an already imbalanced amino acid level. Learn more about the 40 Amino Acids test here: http://www.metametrix.com/test-menu/profiles/amino-acids/amino-acids-40-plasma 4) Comprehensive Organic Acids: http://www.healthegoods.com/organixsm-comprehensive-profile-the-original-organix-urine.html Those with MTHFR commonly have deficiencies in various metabolic pathways. Until these deficiencies are identified and addressed, fatigue, pain and other symptoms linger. This test identifies a variety of useful indicators such as potential candida infection, nutrient deficiency, B vitamins, energy production, fatty acid metabolism and carbohydrate metabolism, bacterial infection, ability to detoxify, #oxidative damage and neurotransmitter metabolism. If a physician simply prescribes you folic acid and aspirin, are they doing the right thing? Are they doing all they need to do? Are you miscarrying? Having blood clots? Suicidal? #Depressed ? Neuropathy? Insomniac? #Autistic ? Then the right thing to do is evaluate YOUR biochemistry and get it on track. Learn more about the Comprehensive #OrganicAcids test here: http://www.healthegoods.com/organixsm-comprehensive-profile-the-original-organix-urine.html 5) Nutrient and Toxic Elements – 24 hour Urine: http://www.healthegoods.com/nutrient-toxic-elements-24-hours-urine.html Those with MTHFR mutations are commonly over-burdened with toxins and infections which deplete nutrients quickly. This test provides insight into which nutrients are specifically low and which heavy metals are being consumed presently. If an individual has elevated urine heavy metal without provocation, then they are experiencing current exposure which must be determined. If a physician ignores present exposures to heavy metals, then they are fighting a raging fire with one bucket of water. I am also of the belief that a physician must address targeted nutrient deficiencies in order to restore cellular function. Learn more about the Nutrient and Toxic Elements test here: http://www.healthegoods.com/nutrient-toxic-elements-24-hours-urine.html 6) #23andMe Gene Test with detailed info on SNPs: 23andMe.com: This is a genetic test which identifies which genes designed for detoxification are not working properly. This is very useful information to know if someone has been detoxing and only feeling worse. It is also a helpful guide for which supplements and medications will work best. It's good to optimize the individual through diet, lifestyle and a specific supplement protocol along with sauna therapy, colonics and/or coffee enemas …and castor oil packs, dry skin brushing, rebounding. You can consolidate many of these tests by ordering just one specific test: Cardio Individualized Optimum Nutrition Profile: http://www.healthegoods.com/cardio-ion-profile-urine.html This profile combines the following tests – just not as complete as ordering them separately: Nutrient and Toxic Elements Amino Acids Essential Fatty Acids Organics Comprehensive Profile Cardiovascular Risk Profile Learn more about the Cardio ION Test here: http://www.metametrix.com/test-menu/profiles/integrated-profiles/cardio-ion NutrEval FMV by Genova is similar to the ION Profile by Metametrix but the information is presented differently. Learn more about the NutrEval FMV test here: http://www.gdx.net/product/10051 Other testing to consider but not absolutely essential right away: Ammonia: not essential because these tests identify the reason why ammonia will be elevated in the first place. (This marker is found in the NutrEval FMV test.) Histamine: not essential because we can see histidine levels which is the precursor to histamine Glutathione: we can deduce if glutathione is low if glycine, cysteine, selenium and glutamine are low. Lipoprotein a: a very bad marker for cardiovascular disease. If this is elevated, it must be lowered to reduce cardiovascular risk. (This is found in the Cardio ION Profile.) Gastrointestinal Testing: not essential because we can see potential yeast, bacterial, viral or fungal infections in the other lab tests. Plus, I always personally address everyone’s digestive function no matter what as I assume it is not optimized anyhow. Why pay for information that I already know is going to be potentially faulty? Lifestyle and dietary changes can make dramatic improvements in digestive function. Supplements may be needed as well – especially probiotics. If no improvement is seen within a few weeks of altering diet, lifestyle and taking suggested supplements, then GI testing may be needed. Leaky Gut Testing: not essential because I personally address it out of the gate anyhow. Everyone has some extent of leaky gut – especially if they consume gluten. If you eat wheat, stop. It is that simple. Yes – everyone needs to stop eating wheat – period. It is a VERY toxic grain and it is increasing autoimmune disease significantly in our country. Even the FDA is working on getting gluten out of all pharmaceutical medications. That tells you something. Stop eating wheat, will you? Heavy Metal Testing: Many with MTHFR mutations are not ready to dive right into heavy metal chelation. Digestive function, mental function, increased energy and basic lifestyle and dietary changes must be addressed before diving right into something as potentially harmful as heavy metal chelation. Once your body is ready to handle the added stress of chelation, then you move to it. Obviously, if you are grossly burdened with heavy metals, perhaps it is best to remove them immediately; however, for the majority of people I have worked with, it is best to improve liver, kidneys, digestion, adrenals and general nutrition prior to chelating. #Pyroluria: This is a condition where people have trouble utilizing zinc and vitamin B6 because of a blood metabolite called kryptopyrroles. Kryptopyrroles come from hemoglobin. If anxiety, depression and other symptoms of mental dysfunction are not improving with MTHFR treatment along with lifestyle and dietary changes, then pyroluria must be considered. #Homozygous #MTHFR #Heterozygous #health #Livewello #23andMe #SNPs #Genes #Methylation http://resqua.com/100002135443410/what-are-some-recommended-laboratory-tests-for-mthfr

1) Biopterin/Neopterin: For those with A1298C mutations, #BH4 (also known as tetrahydrobiopterin) levels are typically quite low. This test provides insight to how low these levels are and why. If neopterin levels are high, then I am considering the possibility of a lingering infection, inflammation or chronic immune response that is preventing #biopterin from being formed. Thus, this test provides information not only potentially low biopterin levels but also why they may be low.

If a doctor simply prescribes BH4 without understanding the need to address the inflammation and chronic infections, it is band-aide treatment over a gaping wound.
Learn more about the Biopterin/Neopterin test here
a) http://www.healthegoods.com...
b) http://www.metametrix.com/t...

2) Urinary #Porphyrins : http://www.healthegoods.com...
Those with MTHFR mutations typically have elevated levels of heavy metals. This test points out the potential of heavy metals without the damaging effects of provoked urinary heavy metal testing. If urinary porphyrins are elevated, then you know you must work with a physician who is very knowledgeable about heavy metal chelation.
If a physician prescribes medications or supplements without addressing heavy metal toxicity at some point, effective treatment for MTHFR cannot exist.
Learn more about the Urinary Porphyrins test here: http://www.metametrix.com/t...

3) Urinary 40 Amino Acids: http://www.healthegoods.com...
Those with MTHFR mutations have many amino acid imbalances. Not only does the Amino Acid test identify amino acids which are imbalanced, but it also informs a knowledgeable physician of other potential mutations. Yes, it is not that easy all the time. I’ve found that while working with MTHFR mutations, I do not get the results I normally see right away. Why? Because there are other mutations present which must be identified and addressed. Amino acids are the backbone of neurotransmitters. If any are low, then symptoms of #ADD / #ADHD, depression, #bipolar , autism and other symptoms are likely present.

If a physician ignores knowing which amino acids are imbalanced, symptoms will linger on and the individual with MTHFR will not recover nearly as quickly. Worse yet, symptoms may worsen if a physician prescribes a medication or supplement which aggravates an already imbalanced amino acid level.
Learn more about the 40 Amino Acids test here: http://www.metametrix.com/t...

4) Comprehensive Organic Acids: http://www.healthegoods.com...
Those with MTHFR commonly have deficiencies in various metabolic pathways. Until these deficiencies are identified and addressed, fatigue, pain and other symptoms linger. This test identifies a variety of useful indicators such as potential candida infection, nutrient deficiency, B vitamins, energy production, fatty acid metabolism and carbohydrate metabolism, bacterial infection, ability to detoxify, #oxidative damage and neurotransmitter metabolism.
If a physician simply prescribes you folic acid and aspirin, are they doing the right thing? Are they doing all they need to do? Are you miscarrying? Having blood clots? Suicidal? #Depressed ? Neuropathy? Insomniac? #Autistic ? Then the right thing to do is evaluate YOUR biochemistry and get it on track.

Learn more about the Comprehensive #OrganicAcids test here: http://www.healthegoods.com...

5) Nutrient and Toxic Elements – 24 hour Urine: http://www.healthegoods.com...
Those with MTHFR mutations are commonly over-burdened with toxins and infections which deplete nutrients quickly. This test provides insight into which nutrients are specifically low and which heavy metals are being consumed presently. If an individual has elevated urine heavy metal without provocation, then they are experiencing current exposure which must be determined.

If a physician ignores present exposures to heavy metals, then they are fighting a raging fire with one bucket of water. I am also of the belief that a physician must address targeted nutrient deficiencies in order to restore cellular function.
Learn more about the Nutrient and Toxic Elements test here: http://www.healthegoods.com...

6) #23andMe Gene Test with detailed info on SNPs: 23andMe.com: This is a genetic test which identifies which genes designed for detoxification are not working properly. This is very useful information to know if someone has been detoxing and only feeling worse. It is also a helpful guide for which supplements and medications will work best. It's good to optimize the individual through diet, lifestyle and a specific supplement protocol along with sauna therapy, colonics and/or coffee enemas …and castor oil packs, dry skin brushing, rebounding.

You can consolidate many of these tests by ordering just one specific test:

Cardio Individualized Optimum Nutrition Profile: http://www.healthegoods.com...
This profile combines the following tests – just not as complete as ordering them separately:
Nutrient and Toxic Elements
Amino Acids
Essential Fatty Acids
Organics Comprehensive Profile
Cardiovascular Risk Profile
Learn more about the Cardio ION Test here: http://www.metametrix.com/t...

NutrEval FMV by Genova is similar to the ION Profile by Metametrix but the information is presented differently.
Learn more about the NutrEval FMV test here: http://www.gdx.net/product/...

Other testing to consider but not absolutely essential right away:

Ammonia: not essential because these tests identify the reason why ammonia will be elevated in the first place. (This marker is found in the NutrEval FMV test.)

Histamine: not essential because we can see histidine levels which is the precursor to histamine

Glutathione: we can deduce if glutathione is low if glycine, cysteine, selenium and glutamine are low.

Lipoprotein a: a very bad marker for cardiovascular disease. If this is elevated, it must be lowered to reduce cardiovascular risk. (This is found in the Cardio ION Profile.)

Gastrointestinal Testing: not essential because we can see potential yeast, bacterial, viral or fungal infections in the other lab tests. Plus, I always personally address everyone’s digestive function no matter what as I assume it is not optimized anyhow. Why pay for information that I already know is going to be potentially faulty? Lifestyle and dietary changes can make dramatic improvements in digestive function. Supplements may be needed as well – especially probiotics. If no improvement is seen within a few weeks of altering diet, lifestyle and taking suggested supplements, then GI testing may be needed.

Leaky Gut Testing: not essential because I personally address it out of the gate anyhow. Everyone has some extent of leaky gut – especially if they consume gluten. If you eat wheat, stop. It is that simple. Yes – everyone needs to stop eating wheat – period. It is a VERY toxic grain and it is increasing autoimmune disease significantly in our country. Even the FDA is working on getting gluten out of all pharmaceutical medications. That tells you something. Stop eating wheat, will you?

Heavy Metal Testing: Many with MTHFR mutations are not ready to dive right into heavy metal chelation. Digestive function, mental function, increased energy and basic lifestyle and dietary changes must be addressed before diving right into something as potentially harmful as heavy metal chelation. Once your body is ready to handle the added stress of chelation, then you move to it.

Obviously, if you are grossly burdened with heavy metals, perhaps it is best to remove them immediately; however, for the majority of people I have worked with, it is best to improve liver, kidneys, digestion, adrenals and general nutrition prior to chelating.

#Pyroluria: This is a condition where people have trouble utilizing zinc and vitamin B6 because of a blood metabolite called kryptopyrroles. Kryptopyrroles come from hemoglobin. If anxiety, depression and other symptoms of mental dysfunction are not improving with MTHFR treatment along with lifestyle and dietary changes, then pyroluria must be considered.

#Homozygous #MTHFR #Heterozygous #health #Livewello #23andMe #SNPs #Genes #Methylation

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