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If it is not already in the Gene Library then:

1) Go to Read about the GWAS tool If a condition is not listed there, solid research connecting genes to that health condition, have not been found or made.

2) Type in the health condition slowly and you'll start to see options pull up. Select the appropriate one. Results showing rsIDs and Genes will pull up. If you'd like a detailed report, we suggest you go through each PubMed citation and click the "Read Pubmed Citation" button. It will open ... ..more

Physicians don't always know what to do with your genetic information because epigenetics and pharmacogenomics are relatively new fields, and everyone is trying to catch up.  Also Traditional/Allopathic physicians have very limited time in which to  go over all the information that you hand over to them, so the best way to present them with new information like this, is to share a link to your Report and make sure you tell them to read the associated medical references that come with your App. For instance, every Gene in the LiveWello Gene App report is directly linked to ... ..more



What are RefSNP Alleles?

  4 years, 5 months ago

RefSNP alleles are the alleles submitted by genetic researchers for a particular SNP. for example CBS C699T has RefSNPs A/G. This means that the researcher found A on one chromosome strand and G on the other, at the gene location for CBS C699T.

RefSNP Alleles for a particular gene location in a genome build, are submitted to dbSNP by multiple genetic researchers. Each SNP will usually only have two RefSNP alleles. When different researchers submit conflicting information about RefSNP alleles, then it is possible for more than 2 alleles to be listed for one SNP, making it more difficult ... ..more

Since copper is important for producing ceruloplasmin, the protein that transports iron in the bloodstream, some of the symptoms of copper deficiency come from a lack of available iron. The most common is anemia, or a low red blood cell count. Copper deficiency can also cause a decrease in white blood cell numbers, which can affect immunity to infection.

Lack of copper also affects the central nervous system and spinal cord and can mimic the symptoms of B12 deficiency. A person deficient in copper may experience demyelination of nerves in the brain and spinal cord, which can lead to sensory ... ..more

Methymalonic acid is the best test currently available ..more


What is pharmacogenomics?

  4 years, 8 months ago

Pharmacogenomics is the study of how genes affect a person’s response to drugs. This relatively new field combines pharmacology (the science of drugs) and genomics (the study of genes and their functions) to develop effective, safe medications and doses that will be tailored to a person’s genetic makeup.

Many drugs that are currently available are “one size fits all,” but they don’t work the same way for everyone. It can be difficult to predict who will benefit from a medication, who will not respond at all, and who will experience negative side effects (called adverse drug reactions ... ..more

Genome-wide association studies are a relatively new way for scientists to identify genes involved in human disease. This method searches the genome for small variations, called single nucleotide polymorphisms or SNPs (pronounced “snips”), that occur more frequently in people with a particular disease than in people without the disease. Each study can look at hundreds or thousands of SNPs at the same time. Researchers use data from this type of study to pinpoint genes that may contribute to a person’s risk of developing a certain disease.

Because genome-wide association studies examine SNPs across the genome, they represent a promising ... ..more

When a genetic disorder is diagnosed in a family, family members often want to know the likelihood that they or their children will develop the condition. This can be difficult to predict in some cases because many factors influence a person’s chances of developing a genetic condition. One important factor is how the condition is inherited. For example:

Autosomal dominant inheritance: A person affected by an autosomal dominant disorder has a 50 percent chance of passing the mutated gene to each child. The chance that a child will not inherit the mutated gene is also 50 percent (illustration).

Autosomal ... ..more

Statistical data can provide general information about how common a condition is, how many people have the condition, or how likely it is that a person will develop the condition. Statistics are not personalized, however—they offer estimates based on groups of people. By taking into account a person’s family history, medical history, and other factors, a genetics professional can help interpret what statistics mean for a particular patient.

Some statistical terms are commonly used when describing genetic conditions and other disorders. These terms include:

Common statistical terms
The incidence of a gene mutation or a genetic disorder ... ..more

A genetic predisposition (sometimes also called genetic susceptibility) is an increased likelihood of developing a particular disease based on a person’s genetic makeup. A genetic predisposition results from specific genetic variations that are often inherited from a parent. These genetic changes contribute to the development of a disease but do not directly cause it. Some people with a predisposing genetic variation will never get the disease while others will, even within the same family.

Genetic variations can have large or small effects on the likelihood of developing a particular disease. For example, certain mutations in the BRCA1 or BRCA2 ... ..more