Sign in to share an answer

"i" numbers are for SNPs that don't correspond to standard rsIDs. 23andMe chose them for probes they designed internally. First you can get their chromosomal position: Then you can find the reference SNPs given that chromosomal position with dbSNP or the UCSC Genome Browser: http://genome.ucsc.edu/cgi-.... However, there often is not a direct correlate. There is no easier way to do this sadly.
An example of the issues with i numbers: https://www.23andme.com/you...
#23andMe #Genes #rsIDs #dbSNP ..more

A slowed down: #MS/MTRR #BHMT #CBS SNPs
Anything causing Homocysteine to build up, back up or slow down the conversion of #Homocysteine into #Methionine .
The #MTHFR C677T mutation is NOT the only cause of elevated homocysteine. ..more

This is a statement from Dr. Iwegbue, Founder and Lead Developer of the Livewello Gene App:

I'd like to share with you the reason why 23andMe Variance Report results sometimes differ depending on the App used. Results are determined by the Minor Allele used:
All of LiveWello's Minor Allele information is retrieved directly from dbSNP. A link to dbSNP is added to every SNP in a Livewello Gene Variance Report. That way, a user and their Practitioner can verify minor allele information for themselves.

At Livewello, we only use the forward strand for interpreting all our SNPs. This ... ..more

To Submit a Request for assistance from 23andMe: https://customercare.23andm...

Using the 23andMe Kit: https://customercare.23andm...

Genetics 101: https://customercare.23andm...

Understanding 23andMe Raw Data; https://customercare.23andm...

How do I find my raw data ?: https://customercare.23andm...-

How do I use Browse Raw Data?: https://customercare.23andm...-

What does No call/Not genotyped mean in Browse Raw Data?: https://customercare.23andm...-

Creating a 23andMe account: https://customercare.23andm...

Resetting your password: https://customercare.23andm...

Confirming your account email address: https://customercare.23andm...

Navigating between profiles: https://customercare.23andm...

Email, Password, Secret Question issues: https://customercare.23andm...

To ... ..more

Annonymous

What is IL4R?

  3 years, 8 months ago

This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, #sinusitus , #asthma , or #eczema . Polymorphisms in this #gene are also ... ..more

#23andme currently only tests for THREE mutations in these genes. So, even if 23andme says you are normal for all three mutations, you could still have a harmful mutation somewhere else in one of these genes. Any harmful mutation means a person has Hereditary Breast/ #OvarianCancer Syndrome.

The three mutations 23andme tests for are found mostly in Ashkenazi (Eastern European) Jews. It just happens that these three mutations are easy to test for and are well-studied.

As a general rule, you are hoping NOT to see DI as the genotype at any of your #BRCA1 and #BRCA2 locations. Genotype DI ... ..more

STEP ONE: Layering in The Foundation
Knowing your Nervous system #dominance is an integral part in establishing the treatment process.
A). Remove or limit triggers:
Processed foods contain excitotoxins, dyes, and #toxic preservatives. It is also crucial to remove obvious food #allergies . Please see Resqua pages on #excitotoxins for more information. This is simply defined and discussed in detail. 



B). Begin general support:
Provide a good foundation for your nervous system type and begin nutritional support. Though life threatening reactions would be extremely rare (and to my knowledge, unheard of), moving too quickly can result in more intense symptoms of ... ..more

 Tags
Thyroid GF/CF Genes Sympathetic enemas ADHD. Gut epinephrine focus muscle mitochondrialdisorder thyroid, supplement sleep zinc Hormones Livewello eyehealth adrenal antacid ammonia mitochondrial discipline L-Methyl homocysteine bloodpressure ACE immune overmethylation paranoia Norepinephrine: folate Norepinephrine livewello health Parkinson’s BRCA1 overeating BRCA2 kidney yeast minerals: SHMT libido dysbiosis Resveratrol C699T headaches biofilms cholesterol, Parkinson's Cholesterol Carnosine minerals VitD TMG Copper neurological glutathione serotonin, aluminum autistic virus. nutrients 23andMe potassium RNA vegetables heart B6 SNS SNP MTRR rsIDs chronicfatigue 23andMe MAO LouGehrig’s VDR Farm-to-table BCMO1 FolicAcid Gooseberry dopamine OCD melatonin Folate Pharmacogenomics schizophrenia Autism Choline Amla bacteria depression irritability Coffee Methyl genetics alcohol Oxalates, sinusitus emotions adrenalin strokes 3 urea excitatory mutation vascular Myasthenia lethargic NitricOxide Dihydrofolate UreaCycle attention Lifestyle cortisol Supplements Dopamine forgetfulness mood kidneystones Supplements peristalasis SAMe oxidative asthma Huntington's UTM detoxification Migraines pregnancy GeneticTesting retinol glutamate lifestyle testosterone MTHHR methylation SNPs RNA A1298C. Epinephrine arrhythmias ADHD CBS MAOA CBS/NOS insulin MS thyroid stress antibiotics perseverative Livewello Ammonia Kidney GABA emotion gambling, gastro cancer lethargy, DigestiveEnzymes antioxidant masticator motivation seizure apathy Cell chronic heartattacks. ACAT B12 learning freeradical Heterozygous glutathione. FM dysfunction Acidophilus 5-MTHF BHMT NitricOxide UEE C677T DNA Diet 23andme MethylDonor hyperactivity genetic RawData digestiveenzymes neurotransmitter gut antioxidants CoQ10 exhaustion Liver MCAD adrenals. DNA gluten MTHFR Acerola Mitochondria organic, Folate undermethylators. serotonin dopamine, ADD histamine liver Plantarum Methylgroups sex colitis Methylation bile fatabsorption BloodPressure toxins autism noradrenaline BHMT POTS centrifugal psychosis metabolism Hypotension/ overmethylators cure probiotics magnesium undermethylators Pancreas Glutamate/ dbSNP allergic ALS B6, nervousness cortisol, acetylcholine estrogen MS/MTRR Alzheimer's Allergies Glutathione coffee metals alertness MTHFD1 stroke hormone eczema Methyltetrahydrofolate leakygut Lithium neurotransmitters BH4 thioredoxin B3 drugs nicotinic gene dementia Anxiety apraxia CFS allergies NonGMO DAO transsulfuration concentration excitotoxins swallowing Alzheimer’s supplements speech preservative hormones toxic anxiety panic dominance speech. Histamine memory Epigenetics Fibromyalgia glutamates nutrigenomics Methylation MTR Tourette's Gene arthritis NOS DHA COMT fungus norepinephrine Stims fatigue juicers Homozygous flushed detox NitricOxide Adrenal diabetes tyrosine lupus AHCY virus Estrogen Methionine Homocysteine enzymes bowel PNS mitochondria sclerosis CFS, Zinc OvarianCancer EDTA A1298C heavymetals adrenaline Sleep methionine parasites organization cholesterol diet Neurotransmitter 5-HTP