The Major Tasks of Methylation
In order to provide a brief overview, the following methylation tasks have been vastly streamlined. In reality, there is an endless array of both direct and indirect Methylation activities within the human body. Even so, this summary should provide greater understanding of this highly complex pathway, as well as the complications that can arise from various defects or toxic exposures.
Methylation is responsible for the following:
1. Nervous system function (brain, spinal cord, & nerve cells). It’s critical for the insulation around nerves (myelin), which allows signals to properly transmit via this sheath, or outer layer.
2. Chemical messengers, or neuro-talkers, that provide the means for communication throughout the community as well as maintaining mood, health, & wellbeing. Methylation yields neurotransmitters such as dopamine, serotonin, melatonin, & norepinephrine.
3. Regulation of gene expression by subduing the corrupt genes and nurturing those that are beneficial.
4. The creation of new RNA and DNA, our genetic building blocks.
5. Direct communication between the nervous & immune systems so that hazards are addressed, thus
thwarting would be attackers.
6. Management of sulfur metabolism, a major contributor within the detoxification system (transsulfuration
7. Mobilizes fat and cholesterol so that they are efficiently removed from the body and/or used
appropriately for the production of hormones, myelin sheath (nerve lining), and bile salts.
8. Hormone control and production. Methylation is instrumental in estrogen, testosterone, & insulin concentrations as well as many other hormones throughout the body.
9. The allergic response including: a). Anaphylactic reactions (life threatening), b). Food or seasonal allergies, c). Eczema & hives, & d). Asthma. This is accomplished through histamine regulation.
10. The production and repair of proteins throughout the body: Four examples include
a). Amino acids (building blocks of protein),
b). Hemoglobin (carries oxygen to body), and
c). Antibody defense such as IgA, IgE, IgG, & IgM (immune factors that defend us from invaders), and
d). Collagen or Elastin, which offer structural function and support within the body via Collagen’s role in connective tissue, (tendons & ligaments), while elastin is found in the intestines, blood vessels (arteries), and lungs.
11. RNA Methylation, as it permits for more accurate instruction to DNA in cell replication & identity.
12. DNA Methylation, which allow cells to operate, as they should whether skin, hair, liver, or brain cells.
13. Cell membrane fluidity, which impacts what goes in or comes out of each cell through its’ outer coating.
This allows cells to fine-tune their own mineral levels, allowing elements to move in & out as needed.
14. Processing and filtering of heavy metals & environmental toxins as well as phenols, glutamates, pesticides, additives, sulfites, ammonia, drugs, herbs/supplements, adjuvants, etc.
15. Oversees the removal of free radicals as well as the formation of new cells to take their place.
16. Regulates histones, the proteins that are tightly wound within the DNA. These are one of the specific
proteins involved in cell division and cancer.
17. Homocysteine (HCY) regulation in order to provide adequate work tags while preventing HCY’s more
harmful effects (inflammation within blood vessels, brain, and heart tissue).
18. The conversion of many nutrients (i.e., folate or HCY) into more active forms (5 MTHF or Methionine)
for more work tags, leading to innumerable actions throughout the community.
19. Production, maintenance, and repair of cells, which leads to peak performance within the nerve, tissue,
and organ as well as healing.
20. BH4 production, which is critical for neurotalkers, waste & toxin cleanup, and nitric oxide production.
￼￼￼￼The latter is used for maintaining open & clean blood vessels as well as protecting the heart & brain.
Does a business analogy with CEO’s, executives, and supervisors seem confusing? Consider methylation as an orchestra, in which each instrument, no matter how minor, has a role to play. While you might not realize that the violin or piano piece is missing, the music appears much less captivating. Moreover, the lost musical pieces lead the other musicians to make errors, thus changing the entire symphony.
#Methylation #23andMe #GeneticTesting #Livewello
How do I generate a report? 20 views
How do I share a profile? 20 views
How do I create a profile? 3 views
How do I use SNP Sandbox? 18 views
What do you test for? 8 views
I am trying to find my results on the BRCA1/BRC2 Gene results tested by 23andMe. How can I do this? 2 views
I get a message that there is no raw data for my profile when I connect the Gene App to 23andMe. What do I do now? 5 views