CBS (cystathionine beta synthase) catalyzes the first step of the transsulfuration pathway, from homocysteine to cystathionine. Dr. Yasko considers addressing CBS mutations as first priority aside from addressing the gut.
This enzyme converts homocysteine to cystathionine. In a separate reaction, cystathionine is then converted to cysteine which in turn goes to taurine or glutathione among other things.
CBS defects are actually upregulations. This means the enzyme works too fast. Therefore, it is common to see low levels of cystathionine and homocysteine since there is a rapid conversion to taurine. This leads to high levels of taurine and ammonia.
The upregulation ... ..more
Understandably, human beings adapt much more readily to positive reinforcement, avoiding the negative experiences. While there are many approaches to #detox , experience has shown that it takes commitment on par with taking a seminar or, when really ill, getting through a longer flu or hospitalization. It takes an extensive amount of time, energy, and dedication, which is often extremely difficult for those who work full-time and/or have a difficult time slowing down. Regardless of the strategy, if you relegate the process to moments of “when I get time,” you cannot be successful. Many make the mistake of trying to ... ..more