Sign in to share an answer

Since copper is important for producing ceruloplasmin, the protein that transports iron in the bloodstream, some of the symptoms of copper deficiency come from a lack of available iron. The most common is anemia, or a low red blood cell count. Copper deficiency can also cause a decrease in white blood cell numbers, which can affect immunity to infection.

Lack of copper also affects the central nervous system and spinal cord and can mimic the symptoms of B12 deficiency. A person deficient in copper may experience demyelination of nerves in the brain and spinal cord, which can lead to sensory ... ..more

Since copper is important for producing ceruloplasmin, the protein that transports iron in the bloodstream, some of the symptoms of copper deficiency come from a lack of available iron. The most common is anemia, or a low red blood cell count. #Copper deficiency can also cause a decrease in white blood cell numbers, which can affect immunity to infection.

Lack of copper also affects the central nervous system and spinal cord and can mimic the symptoms of B12 deficiency. A person deficient in copper may experience demyelination of nerves in the brain and spinal cord, which can lead to sensory ... ..more

5 “Healthy” Foods That Aren’t
January 15, 2014 by Erin Ter Beest

In a world of competing health claims, it’s hard to know what foods are really nourishing and health-promoting. Sometimes it’s even hard to tell whether or not something is really food or just a “food-like substance!” While the occasional #junk food isn’t going to kill you (and stressing out about completely avoiding it might actually do more damage than the occasional junk food itself), there are many “health” foods that have made their way into our diets regularly that are doing serious damage to ... ..more

Annonymous

What is the Methionine Cycle ?

  4 years, 1 month ago

The Methionine Cycle is the major work tag (methyl donor) manufacturer. SAMe has over 400 functions in the community. Also serves as the main route through to liver & Waste cycle.

Methionine (SAM) Cycle AKA “SAM’s Corporation,” As SAMe has over 400 known methylation reactions, SAM’s Corporation is the chief work tag producer. It’s also where most of the action occurs since it contains the major thoroughfare to the liver (CBS & transsulfuration). While this often works to its’ advantage, it can also pose a safety risk since failure along this route may result in calamity (see Waste Facility ... ..more

The recommendations to work on CBS is b6 active form p5p and molybdenum to balance copper and zinc and help break down excess sulfates. You can get some sulfate strips these ones http://www.amazon.com/gp/aw.... You want to get your urine sulfates down to at least 800 preferably 400 before adding in methylfolate and methylb12. ..more

This question is hidden

From: http://www.stopthethyroidma...
"As explained well in the revised STTM book, which you should have on hand and bookmarked at the doctors office. The book is in English, Spanish, German and Swedish.

TSH: for diagnosis of hypopituitary, NOT to diagnose or dose your hypothyroidism (unless it’s high). If you allow a doctor to diagnose or dose you by this lab test and range i.e. to say you are normal simply because it’s in range or below 10…you’ll could still be hypothyroid.
Free #T4 and Free #T3 (note the word “free”–important since it measures ... ..more


It produces a defective MTHFR enzyme of different varieties i.e. it functions less than optimally, such as performing at only 40% of its capacity, or 70% of its capacity. It can mean you won’t break down toxins or heavy metals well i.e. you could find yourself with high iron, or high copper, or high mercury….etc. High copper can also cause low iron.
The defective enzyme doesn’t break down folate vitamins properly (of which folic acid is the precursor to), which can cause high homocysteine, which can increase your risk of coronary heart disease (arteriosclerotic vascular ... ..more

MAO-A (Monoamine oxidase A) is a critical enzyme involved in breaking down important neurotransmitters such as serotonin, norepinephrine, and dopamine. While a homozygous (+/+) mutation is very common, prolonged periods of stress, violence, or trauma can lead to epigenetic changes that further decrease enzyme activity. On the table above, males only have one allele since the gene is inherited through from their mother since it is located on the X chromosome.
Males are more likely to have this mutation, represented on the table as homozygous (+). Only females can be heterozygous (+/-) for this mutation.

When a (+/+) MAO-A mutation is combined with a ... ..more

Annonymous

What does a CBS Gene Mutation mean ?

  4 years, 1 month ago

CBS (cystathionine beta synthase) catalyzes the first step of the transsulfuration pathway, from homocysteine to cystathionine. Dr. Yasko considers addressing CBS mutations as first priority aside from addressing the gut.
This enzyme converts homocysteine to cystathionine. In a separate reaction, cystathionine is then converted to cysteine which in turn goes to taurine or glutathione among other things.

CBS defects are actually upregulations. This means the enzyme works too fast. Therefore, it is common to see low levels of cystathionine and homocysteine since there is a rapid conversion to taurine. This leads to high levels of taurine and ammonia.

The upregulation ... ..more

You wanna work on cbs first because it's an upregulation when you start adding methylfolate and methylb12 and you don't have cbs under control all of the folate and b12 will used up down the cbs pathway instead of being recycled in the methylation pathway. It's a kind of a big balancing act. But once you start finding the right balance and getting better you will start to see the positives. The big ones I use for cbs is b6 active form p5p and molybdenum to balance copper and zinc and help break down excess sulfates. You ... ..more

CBS C699T cystathionine beta synthase AKA The Hole in the Bucket. This Priority # 3 Mutation
Tip! It is crucial to address any gut issues before you thoroughly address the CBS defect. Since chronic gut issues lead to higher bacterial loads, thus leading to higher ammonia production as well as leaky gut (reducing nutrient absorption and increased risk for food sensitivity) this area is paramount. You can begin to address the CBS prior to fully addressing gut issues though they should be done in concert. Since the CBS is one of the most important issues to address, I’ve decided to ... ..more

http://balancedconcepts.net...
Details of Liver Functions
The liver has a number of important functions, some of the main ones being:

Detoxification of potentially toxic chemicals from both inside and outside of the body including
drugs, alcohol and toxins from intestinal microbes. Accomplished with antioxidant nutrients
and enzymes such as glutathione. The liver detoxifies these harmful substances by a complex series of chemical reactions. The role of these various enzyme activities in the liver is to convert fat soluble toxins into water soluble substances that can be excreted in the
urine or the bile depending on the particular characteristics of ... ..more

Tylenol/Acetaminophen, Copper, iron, taurine, *calcium, plain folate & folic acid, glycine, glutathione, and “chelated minerals” as these mineral versions often contain one of the following: aspartic acid/aspartame, glutamic acid/glutamate/Monosodium glutamate(MSG), which are all excitotoxins. *Those who are parasympathetic Dominants will probably require calcium, as will those who are closer to recovery once excitotoxicity is well regulated.
#Methylation  ..more