1) Get a Standard Health Report. Go to https://livewello.com/snps and upload your raw data gene results file.
How does the Livewello App work with your Genetic Raw Data?
2) Get a Healthcare Practitioner who is qualified and understands Epigenetics.
Share your Report with your Healthcare Practitioner
Since a software application doesn't know your unique symptoms, your other functional lab levels and a host of your other important health variables, it would be unsafe for it to dispense a safe treatment plan without this information. What you'll need next is ... ..more
COMT, GAD, MAOA/B and addressing methylation too soon can definitely cause neuro-psych issues, but it all comes back to methyl pooling. SNPs in these genes can also contribute: ACE, DAO, MTHFR (e.g., A1298C). Homozygous or 'AA' results for COMT V158M is particularly associated with anxiety & startle response. Quite a few SNPs & quite a few medical conditions can contribute to anxiety, of course (e.g., gut health & bacteria resulting in toxin exposure).
For brain fog / concentration issues, follow up on SNPs affecting ammonia (such as NOS gene, etc.) & BH4 levels (DHPR gene, etc.), also.
With anxiety as a chief ... ..more
SYMPTOMS OF TOO MUCH HISTAMINE
“Histamine is an organic nitrogenous compound involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter. Histamine is involved in the inflammatory response.” [wiki]
FOR MORE INFORMATION:
After eating certain histamine aggravating foods or when there is an excessive quantity of released HISTAMINE in the body symptoms may include:
Menstrual pain [worse]
Rhinitis [vasomotor rhinitis]
DIAMINE OXIDASE [DAO]
Reduced function of the enzyme Diamine ... ..more
HISTAMINE AND THE GUT By Carol Savage M.D.
Diamine Oxidase (DAO) is the enzyme in the gut responsible for the degradation of HISTAMINE.
Histamine N-MethylTransferase [HNMT] is an enzyme found inside cells so it breaks down histamine within cells. Diamine Oxidase [DAO] is likely “responsible for scavenging extracellular histamine after mediator release.”
Although Diamine Oxidase [DAO] is found everywhere in the body, the bowels are perhaps the most important site of the action of the enzyme DAO.
DAO is synthesized by mature and undamaged enterocytes [gut cells] in the small bowel, so any gut damage would decrease DAO release ... ..more
From Dr Carol Savage:
DIAMINE OXIDASE [DAO]…HISTAMINE
Histamine is a very important molecule for the human body because it fulfils many vital functions, but too much is not good. Histamine is both produced in the body and taken in with the ingestion of various foods.
Problems develop when there is an EXCESSIVE amount of HISTAMINE or when it is not adequately degraded. In either case histamine will lead to allergic or “Pseudo-allergic Reactions” [reactions that appear to be allergic in nature but are not].
S-Adenyl Methionine [SAMe] is needed to inactivate histamine in ... ..more