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Annonymous

How can I stimulate my vagus nerve

  2 years, 11 months ago

SOURCE: http://selfhacked.com/2015/...


Introduction to The Vagus Nerve

In people with fatigue, food sensitivities, anxiety and gut problems, brain fog and depersonalization, the vagus nerve is almost always at play. These people have lower vagal tone, which means a lower ability of the vagus nerve to activate.

The only question is what aspect of the vagus nerve is malfunctioning and how much the vagus nerve is a problem vs. other aspects of your biology.

The vagus nerve is part of the parasympathetic nervous system, referred to as the rest and digest system. It’s not the only nerve ... ..more

*Circulatory & blood clotting factors
*DNA synthesis & repair via thymidine synthesis
*Gene expression via epigenetic regulations such as histone modification
*Nitric oxide synthesis, aka blood vessel elasticity
*Removal of homocysteine, a potentially toxic and atherogenic amino acid
*Synthesis of powerhouse antioxidants such as Glutathione & SOD
*Neurotransmitter synthesis & degradation - dopamine, serotonin, norepinephrine, glutamate, GABA
*Biotransformation (aka “metabolism & detoxification”) of chemicals, carcinogens & drugs
*Synthesis of immune cells
*B-12 & Folate utilization
*Organ, tissue and fetal development

While their program is expensive it does seem like it would really make one a kind of expert.

Now if I could just find common, insured tests for ... ..more

Annonymous

What is MTHFR A1298C Gene Mutation ?

  4 years, 2 months ago

By Helen Janneson Bense

A1298C single nucleotide polymorphism (SNP) affects the enzyme known as 5,10 MethyleneTetraHydroFolate Reductase (MTHFR). This polymorphism involves a down regulation of the MTHFR enzyme, responsible for the backwards reaction of the folate cycle, where 5-methylfolate (5MTHF) is converted into tetrahydrofolate (THF). This reaction is most important for the production of BH4 – tetrahydrobiopterin. Each turn of the folate cycle and conversion of 5MTHF to THF produces 1 molecule of BH4. In heterozygous and homozygous states, enzyme activity will be compromised by
approximately 30% and 70% respectively.

Functions of BH4
Cofactor for all three isotypes of nitric ... ..more

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Annonymous

How does Methylation influence mood ?

  4 years, 6 months ago


It is important to understand the basics of methylation, and although a more detailed study of #methylation chemistry may be interesting, for our needs, it is not really necessary to study it here as it will only serve to confuse matters, so only the most important aspects will be considered.

Put simply, the methylation process makes #neurotransmitters (mood building blocks), and the issue of a person being an under or over methylator can be confusing, because there is contradiction between the various sources of information on the methylation process. For our purposes, we'll say that an over methylator is ... ..more

Consistently elevated glucose
Consistently low glucose
Elevated triglycerides
VDR Fok Ff ( -+) or VDR Fok f f (+ +)
Imbalances in pancreatic elastase on a CSA/GI Profile
Imbalances in chymotrpsin values on a CSA/GI Profile
Imbalances in SCFA (Iso-butyrate, iso-valerate and n-valerate) on CSA/GI Profile
Imbalances in LCFA on a CSA/GI Profile

Supports for Pancreatic Health:
Prolongevity Formula RNA
CCK Support Formula RNA
VDR FOK Compounded Supplement
Vita D-Light Spray OR Vitamin D
Special Digestive Enzymes With Each Meal
Fenugreek
Chromium
Red Rice Yeast
Vanadyl
GABA
 ..more

Annonymous

How can I care for my Pancreas

  4 years, 6 months ago

Lab Tests indicating a need for Pancreatic Support:
Consistently elevated glucose
Consistently low glucose
Elevated triglycerides
#VDR Fok Ff ( -+) or VDR Fok f f (+ +)
Imbalances in pancreatic elastase on a CSA/GI Profile
Imbalances in chymotrpsin values on a CSA/GI Profile
Imbalances in SCFA (Iso-butyrate, iso-valerate and n-valerate) on CSA/GI Profile
Imbalances in LCFA on a CSA/GI Profile

#Supplements for #Pancreatic Health:
Prolongevity Formula RNA
CCK Support Formula RNA
VDR FOK Compounded Supplement
Vita D-Light Spray OR Vitamin D
Special Digestive Enzymes With Each Meal
Fenugreek
Chromium
Red Rice Yeast
Vanadyl
#GABA
#Methylation ..more

#Neurotransmitter
Lab Tests indicating a need for #Glutamate #GABA balance:
Elevated glutamate, #glutamine #glutamic acid on urine AA test
Elevated #aspartate #aspartic acid on urine AA test
Low GABA (gamma aminobutyric acid) on a urine AA test
Low GABA on a Neurotransmitter test
Elevated #quinolinic on #OAT #Metabolic Test
#Seizures
#Stims
Poor eye contact
#Aggressive behavior

#Supplements to balance Glutamate and GABA:
Nerve Calm Formula RNA
Comfort RNA
Be Calm Glutamate Spray/Gaba Spray
Melatonin Sleep Spray
#Progesterone cream- Pro-Gest Body Cream
GABA
Pycnogenol
Grape Seed Extract
Valerian Root
Jujube
#Lithium Orotate based on UEE levels
L-Theanine
Taurine (not for ... ..more

Elevated #glutamate , glutamine, glutamic acid on urine AA test
Elevated aspartate, aspartic acid on urine AA test
Low #GABA (gamma aminobutyric acid) on a urine AA test
Low GABA on a Neurotransmitter test
Elevated quinolinic on OAT/Metabolic Test
#Seizures
#Stims
Poor eye contact
#Aggressive behavior

Supports to balance Glutamate and GABA:
Nerve Calm Formula RNA
Comfort RNA
Be Calm Glutamate Spray/Gaba Spray
Melatonin Sleep Spray
Progesterone cream- Pro-Gest Body Cream
GABA
#Pycnogenol
Grape Seed Extract
Valerian Root
Jujube
#Lithium Orotate based on UEE levels
L-Theanine
Taurine (not for CBS + or SUOX Mutation unless suggested on testing)

#supplements ..more

1). #MTHFR #A1298C + #Liver & #BH4 support
Start at a few crumbs per day and very gradually, go up over several weeks’ time (generally 4-6 weeks). The goal is 1⁄2 to 1 capsule daily ($54.95/60 caps & $29.95/30 caps). This is whether you have the MTHFR A1298C defect or not.

2). Black Bear Spray or Get B12 Spray
Start at 1-2 sprays per day and very gradually work up to 3-5 sprays once or twice daily. A tip for adults who develop headaches with wine, it is very likely that you are sensitive to sulfites and the ... ..more

The following are the most important issues to address as soon as you can:
Dietary changes: Reducing neurological irritation and achieving Glutamate #GABA balance is critical!
1). Excitotoxins: The more excitotoxins you have coming into your body will only serve to undo many of the helpful measures you’ve already implemented as well as those below. Therefore, I highly recommend a gluten (wheat, rye, barley), casein (*dairy), & soy free diet. See the attached sheets/PDF regarding dietary guidance. In the end, you can only do the best that you can so if finances do not permit this, simply avoid these ... ..more

Annonymous

Any thoughts on MTHFR and Lithium ?

  4 years, 6 months ago

#MTHFR #Lithium
Lithium has been known for years to be useful for #bipolar disorder. Despite all that is known about lithium and its impact on biochemical pathways, no one has defined the mechanism by which lithium has its impact on bipolar disorder. It is likely to be an effect on multiple pathways. There are a number of enzymes in the body that are known to be impacted and inhibited by lithium.

Lithium comes together with methylation at #COMT, the enzyme catechol-o-methyl-transferase. COMT breaks down #dopamine and #norepinephrine. Dopamine is a critical #neurotransmitter for motivation, focus and attention, among other functions ... ..more

Annonymous

What is Homocysteine ?

  4 years, 6 months ago

#Homocysteine is a toxic waste by-product of protein and amino acid metabolism, and #methylation in the body is going on constantly, converting this damaging homocysteine into the #antioxidant #glutathione.
Methylation also converts homocysteine into an important biochemical called #SAMe , a vital methyl donor for the production of the all important neurotransmitters dopamine, serotonin and their derivatives. This is how the body makes good use of this toxic element.

Keeping homocysteine at a healthy, low level is extremely important for keeping our risk of heart disease, stroke and Alzheimer's disease as low as possible. High levels of homocysteine, if left ... ..more

Annonymous

What is Glutamate ?

  4 years, 6 months ago

Glutamate is the major excitatory #neurotransmitter and the most commonly found NT in the brain. It is required for #learning and #memory , however, an excess of #glutamate is actually toxic to brain cells and nerves. #LouGehrig’s is the most well known disease of glutamate excess but newer evidence reveals many other disorders may be related such as #Autism , #CFS, many #seizure disorders, #Migraines , #MS , and many more. Glutamate balances #GABA ’s calming effect.
High levels can cause nerve and brain cell death and injury through inflammation. High or imbalanced glutamate levels are clearly involved in many neurological diseases such ... ..more

Understandably, human beings adapt much more readily to positive reinforcement, avoiding the negative experiences. While there are many approaches to #detox , experience has shown that it takes commitment on par with taking a seminar or, when really ill, getting through a longer flu or hospitalization. It takes an extensive amount of time, energy, and dedication, which is often extremely difficult for those who work full-time and/or have a difficult time slowing down. Regardless of the strategy, if you relegate the process to moments of “when I get time,” you cannot be successful. Many make the mistake of trying to ... ..more

Calcium below the range of low end normal on a urine essential test
Calcium below the range of low end normal on a RBC element test
High level excretion of lead should check urine calcium levels

Supports to increase Calcium:
Bone Support Formula RNA
MitoForce Compounded Supplement
CoEnzyme Q10 Fatigue & Muscle Support Spray
GSH Capsules
Nettle (In Calm Down-Gaba/Glutamate Spray)
#Chamomile
Chervil
Cal/Mag/VitD/VitK -Calcium & Magnesium Citrates
Don Quai - Max V
Black Cohosh
Prevagen 5mg or less
 ..more