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Since a software application doesn't know your unique symptoms, your other functional lab levels and a host of your other important health variables, it would be unsafe for it to dispense a safe treatment plan without this information. What you'll need next is ... ..more

HISTAMINE AND THE GUT By Carol Savage M.D.
Diamine Oxidase (DAO) is the enzyme in the gut responsible for the degradation of HISTAMINE.

Histamine N-MethylTransferase [HNMT] is an enzyme found inside cells so it breaks down histamine within cells. Diamine Oxidase [DAO] is likely “responsible for scavenging extracellular histamine after mediator release.”
Although Diamine Oxidase [DAO] is found everywhere in the body, the bowels are perhaps the most important site of the action of the enzyme DAO.
DAO is synthesized by mature and undamaged enterocytes [gut cells] in the small bowel, so any gut damage would decrease DAO release ... ..more

~FREE and Unlimited Access to the NEW Livewello SNP Sandbox tool.
With this feature, you can now add up to 250,000 SNPs to your Gene Report.
You now have the power to find out more about SNPs that are not included in other Standard Variance Reports.

~FREE SNP Library accessible at https://livewello.com/snp/l...
This is an example of a Livewello user's shared SNP Template using SNP Sandbox:
Histamine Template (HNMT SNPs): https://livewello.com/conne...

~FREE Compare Report Feature: Your Livewello Gene App allows you to compare and view 2 people's Gene Reports side ... ..more

The #MTHFR mutations can affect the proper function of the immune system, and allergies are a result of immune system dysfunction.

There are many ways that the Methyltetrahydrofolate Reductase [MTHFR] enzyme can weaken the immune system, but I do know that if we do not have enough #SAMe then we cannot deactivate Histamine via the #Histamine N-MethylTransferase [ #HNMT ] enzyme.
If Histamine cannot be inactivated then the symptoms of excess HISTAMINE will be perpetuated.
You can find your Histamine Gene status on your #23andMe Gene Test ..more

Annonymous

What is Histamine ?

  4 years, 6 months ago

#Histamine is most commonly known for it's role in #allergic reactions but it is also involved in other neurological functions and can affect your #emotions as well as behavior. Histamine helps control the #sleep -wake cycle and promotes the release of epinephrine and #norepinephrine . This may be the explanation for red ears and #flushed cheeks in susceptible children and adults with high histamine levels.
High levels have been linked to obsessive-compulsive ( #OCD ) tendencies, #depression , and #headaches . Low levels can contribute to #paranoia , low #libido , #fatigue , and multiple medication sensitivities.
it is important to consider that those with the #CBS ... ..more


As far as I know the MTHFR mutations can affect the proper function of the immune system, and allergies are a result of immune system dysfunction.

PICTURE: Allergic orbital edema and conjunctivitis

From Dr. Carol Savage
I do not know all the ways that the Methyltetrahydrofolate Reductase [MTHFR] enzyme can weaken the immune system, but I do know that if we do not have enough SAMe then we cannot deactivate Histamine via the Histamine N-MethylTransferase [HNMT] enzyme.

If Histamine cannot be inactivated then the symptoms of excess HISTAMINE will be perpetuated.
#Homozygous #MTHFR #Heterozygous #health #Livewello #23andMe #SNPs #Genes #Methylation ... ..more