“ #23andme currently only tests for THREE mutations in these genes. So, even if 23andme says you are normal for all three mutations, you could still have a harmful mutation somewhere else in one of these genes. Any harmful mutation means a person has Hereditary Breast/ #OvarianCancer Syndrome.
The three mutations 23andme tests for are found mostly in Ashkenazi (Eastern European) Jews. It just happens that these three mutations are easy to test for and are well-studied.
As a general rule, you are hoping NOT to see DI as the genotype at any of your #BRCA1 and #BRCA2 locations. Genotype DI ... ..more