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By Carol Savage
"Is it possible for people to be low in L-Methyl Folate [5-MTHF] even if they do NOT have single nucleotide polymorphisms affecting the MTHFR enzyme?"

The answer is... YES.

DIET
A person can have terrible nutrition. Someone who doesn't eat anything green. Someone who never eats beans. A poor diet low in DiHydroFolate [DHF] can cause there to be insufficient L-Methyl Folate.

MEDICATIONS
This includes thousands of people on coumadin [warfarin] who avoid eating greens and people with Rheumatoid Arthritis [RA] who have been given Methotrexate. Methotrexate blocks the enzyme that converts DHF into TetraHydroFoalte [THF ... ..more

By Carol Savage
"Is it possible for people to be low in L-Methyl Folate [5-MTHF] even if they do NOT have single nucleotide polymorphisms affecting the MTHFR enzyme?"

The answer is... YES.

DIET
A person can have terrible nutrition. Someone who doesn't eat anything green. Someone who never eats beans. A poor diet low in DiHydroFolate [DHF] can cause there to be insufficient L-Methyl Folate.

MEDICATIONS
This includes thousands of people on coumadin [warfarin] who avoid eating greens and people with Rheumatoid Arthritis [RA] who have been given Methotrexate. Methotrexate blocks the enzyme that converts DHF into TetraHydroFoalte [THF ... ..more

Annonymous

What is GWAS?

  3 years, 11 months ago

Genome wide association studies as a methodology for studying complex genetic traits in humans - successes and limitations
Genome Wide Association Studies were first proposed in the mid-1990s as a way to study association between human genetic polymorphisms and complex, multigenic traits. Rather than measure all genetic variation present in each individual, approximately one million Single Nucleotide Polymorphisms (SNPs) are assayed as genetic landmarks, and scored for association with the trait of interest. Based on linkage disequilibrium, genes in close proximity to associated SNP landmarks are potential candidates for further investigation.

This technique is well-suited to identify susceptibility genes that are ... ..more

Adverse reactions to fluoroquinolone #antibiotics ( #Cipro #Ciprofloxacin #Levaquin #Levofloxacin #Avelox #Moxifloxacin and #Floxin #Ofloxacin ) can manifest in patients as a multi-symptom chronic illness that most resembles #fibromyalgia #chronic fatigue syndrome #CFS / #myalgic encephalopathy (ME) and/or an #autoimmune diseases. As is the case with those chronic multi-symptom illnesses, the symptoms of fluoroquinolone toxicity vary greatly from one individual to another. Though almost everyone who suffers from fluoroquinolone toxicity has some sort of musculoskeletal issues (fluoroquinolones have a black box warning about the risk of tendon rupture), #neuropathy and autonomic nervous system dysfunction, those broad categories of symptoms are where the ... ..more

Annonymous

What is an Excitotoxin ?

  4 years, 3 months ago

#Excitotoxins excite the nerve or brain cell to death.

MSG/Glutamates Please do not attempt to eliminate every last version of #MSG from your diet or you’ll be absolutely insane by the end of the month, it is much too difficult. Just be mindful that there are a lot of hidden ingredients everywhere If a restaurant says they have no MSG in their food, they are almost always referring to the fact that they don’t add MSG to their food but it comes in vats that way already. Also, there are loopholes so that food manufacturers may label ... ..more

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