You have been diagnosed with a chronic health condition. Your genetic information will help you determine which genes or biochemical pathways were altered to result in that health condition. Getting to the root cause, will help facilitate recovery by tailoring any treatment plans and lifestyle changes your Doctor recommends specifically to your body.
Several members of your family live with one or several chronic health issues. Genetic information will help your family uncover the inherited Gene sequence patterns that contribute to the chronic illnesses plaguing them.
You plan to have a baby: Research is implicating certain genetic mutations in a ... ..more
SENSITIVITY TO METHYL DONORS By Carol Savage
Those who are very sensitive to methyl donors have to supplement with low dosages of different kinds of B12 and folate. Rotating them is likely the best approach.
They need to give their body TIME of accept the supplements, TIME to allow the biochemistry to adjust before adding in more...sometimes even skipping days when no supplements are taken.
A gentle approach is the best way to proceed if you are sensitive to methyl donors.
#Methyl Donors #MTHFR ..more
MTHFR and L-METHYL FOLATE… Some Basic Information By Carol Savage M.D.
If you have the MTHFR Gene Mutations C677T and or A1298C and are already taking some L-Methyl Folate [5-MTHF] and Vitamin B12 you might also consider the following:
FOOD Eat plenty of Green Vegetables and beans to get some Dihydrofolate [DHF] and Vitamin B2 [Riboflavin] and many other naturally occurring minerals and vitamins that the body needs etc.
DIHYDROFOLATE [DHF] Dihydrofolate is needed to provide the earlier FOLATE PATHWAYS [the reactions that occur prior to the MTHFR enzyme] with the kinds of folates that they need in order ... ..more
A health village is a group of people involved in your health and wellbeing. They can be family members, friends, teachers, mentors, neighbors and of course your healthcare practitioners. Once you identify them, consider creating a health village by getting a free livewello health acc at:
Then, add each of these people as your health village members. . With your permission, anyone who is your health village member can add/edit supplements, medications etc. This is helpful if for example, your Dr is a member of your health village.
Make sure you add other important information about your ... ..more
1) You have been diagnosed with a chronic health condition.
Your genetic information will help you determine which genes or biochemical pathways altered to result in that health condition. Getting to the root cause, will help facilitate recovery by tailoring any treatment plans and lifestyle changes your Doctor recommends specifically to your body.
2) Several members of your family live with one or several chronic health issues.
Genetic information will help your family uncover the inherited Gene sequence patterns that contribute to the chronic illnesses plaguing them.
3) You plan to have a baby.
Research is implicating certain genetic mutations ... ..more
Lab Tests indicating a need to increase #Calcium:
#Calcium below the range of low end normal on a urine essential test
Calcium below the range of low end normal on a RBC element test
High level excretion of #lead should check urine calcium levels
Supplements to increase Calcium:
Bone Support Formula RNA
MitoForce Compounded Supplement
CoEnzyme Q10 Fatigue & Muscle Support Spray
Cal/Mag/VitD/VitK -Calcium & Magnesium Citrates
Don Quai - Max V
#Prevagen 5mg or less
ACAT Acetyl-Coenzyme A acetyltransferase AKA A bad Gut & Oxalates issues. This is Priority mutation # 2.
Although this mutation is fairly uncommon, it significantly impacts the Energy Cycle (citric acid cycle) and mitochondrial function. The influences are wide and far ranging and include bile salt production, cholesterol, fatty acids, and the processing of oxalates. Notwithstanding a partial or full defect, many have a “functional” variation due to the impact of aluminum, heavy metals, and toxins as well as other defects that impact this area such as the NOS, MTHFR, & CBS. Upon viewing the methylation community diagram, it is important to note that the energy cycle is closely connected to each sequence, yet it is intimately linked to both the waste cycle and SAM’s Corporation.
Since the energy cycle is essential for processing and converting all dietary nutrients (glucose, fats, proteins) into useable forms of energy, a breakdown anywhere down the line might trip an internal alarm. This is analogous to your car’s “low fuel” gauge. Just as any industry processes coal, gas, or oil for energy production, your body must have the essential nutrients in order to properly function. If you visualize the energy cycle as a clock, each hour represents an area in which one nutrient or substance converts into a more compatible form of energy. Depending on digestive function, diet, rate of absorption, and the presence of any genetic quirks, a problem might occur at any point within the device. This may lead to significant chemical imbalances within your body chemistry as well as mitochondrial dysfunction or disorders.
The ACAT plays a key role in creating bile salts, which is crucial for cholesterol and other membrane lipid balances. While we tend to view cholesterol and other fats as the “bad guys” in the war against disease, these compounds are critical for general health and wellbeing. Whether it’s the coating surrounding a nerve, cell, or organ, cholesterol is essential in its production. Think of your home’s electrical wiring and the thick, plastic or rubber coating normally found protecting it. An exposed wire is vulnerable and may “short out,” so that the impulse isn’t transmitted. Similarly, the body’s nervous system requires the protection afforded from a nice, thick fatty coating or fundamental connections may never be made. An exposed nerve may lead to a misfire, which is often the source behind the early symptoms found in neuroimmune disorders. This often includes signs such as tremors, muscle fasciculations, weakness, and fatigue as well as word groping and poor concentration and retention. Without cholesterol, you also cannot make several vital hormones, including, your sex hormones (estrogen & testosterone) or insulin. Therefore, low cholesterol levels are not as beneficial as one would initially think.
Finally, if a chronically ill person has had heavy aluminum or other toxic exposures along with a partially functioning ACAT, energy production is likely to stall to a near standstill. Moreover, as outlined in the energy cycle, other problems may include:
1. More B-12 depletion, which has ramifications throughout the entire system.
2. Cholesterol & fatty acid imbalances, often leading to toxic fatty acid buildup & high cholesterol.
3. Decreasing bile salts & increased taurine production as well as poor cell wall function since they all rely
on the proper breakdown of cholesterol through the ACAT.
4. Poor breakdown of fats, carbohydrates, & proteins to fuel other cells, nerves, tissue, & organs.
5. Rising oxalate levels that may cause painful urination and bladder & kidney stones.
6. Co Q-10 reduction, which is also necessary for mitochondrial function & energy.
7. Limited energy for the Waste Facility & SAM’s Corp. due to less conversion of methionine to SAMe. In
having over 400 methylation functions, SAMe is critical for the entire community.
As the energy factories of each cell, mitochondrial damage has significant implications. In fact, anything that demands more energy, including the gut and the brain, are particularly vulnerable. Significant blocks may limit the availability of bile salts; hence the digestive process is doubly burdened. This provides a valid reason for many unexplained digestive problems, while explaining poor growth & development as well as failure to thrive. Well-studied toxins such as aluminum, lead, mercury, and MSG also greatly impact this factory. This is one reason those with known mitochondrial disorders are discouraged from eating foods with pesticides, MSG, and aluminum. Ultimately, anyone with multiple risk factors is especially prone to mitochondrial dysfunction.
Monitor for oxalates, high taurine, MMA, and/or methionine levels as well as low cholesterol.
Ethanolamine and the ... ..more
1. Start eating 'clean'. Organic, non-GMO home made meals should become a priority. Eliminating #gluten and dairy to relieve your body from the burden of processing them should also begin.
2. Avoid taking any extra Folic Acid. There is already a lot of it in the nation's food supply, as it is added to [fortified] to many processed foods. If a person has the #MTHFR mutations then #L-Methyl Folate is the better choice. Choose this #supplement carefully.
Folic Acid will get turned into #Dihydrofolate and will be all gone, except for any more you may eat due to ... ..more
Lab Tests indicating a need to decrease #Calcium :
Elevated calcium relative to magnesium on a urine essential element test
Elevated calcium relative to magnesium on a red blood cell element test
#Supplements to help address high Calcium:
MitoForce Compounded Supplement
CoEnzyme Q10 Fatigue & Muscle Support Spray
Boswellia -Ayur Boswellia Serrata
Don Quai - Max V
Prevagen 5mg or less ..more
Lab Tests indicating a need for #Liver Support:
Elevated AST (SGOT)
Elevated ALT (SGPT)
Elevated alkaline phosphatase (ALP)
Elevated lactate dehydrogenase (LDH)
Long term chelation with sulfur based chelating agents
High level excretion of toxic metals on fecal tests
#Supplement for Liver Health:
Organ/Liver Support Formula RNA
MTHFR A1298C+/Liver Support BH4 Compounded Supplement
Ultimate B Complex
Cod Liver Oil -CLO
Shark Liver Oil - Norwegian Shark Liver Oil
#Quercetin 500 Plus
#bloodsugar #diabetes diet #glaucoma #glucose #insulin #vitaminc
Diabetes and Glaucoma: A New Perspective
A study at the University of Michigan found people with diabetes have a 35% higher chance of having Glaucoma than people who do not. The study went on to say the reason for the higher rates of glaucoma in diabetics is “unknown.” My purpose for writing this article is to explain the nutritional reasons that diabetes and glaucoma often go hand in hand.
Before going further, let me state this very clearly: The purpose of this article is to provide education. Both diabetes and glaucoma are serious ... ..more
The Vitamin-D controversy…
by ADMIN on APRIL 7, 2013
As anyone who has read my regular posts online, you have learned that I am one of few wellness guys who isn’t ga-ga over Vitamin-D. It’s not the 1st time that I’ve cut against the grain in my career, but I want to offer an explanation that will hopefully explain my counter-cultural rationale…
In my humble opinion, Vit-D is the most misunderstood, but over-recommended supplement on the Planet. What is worth noting is that it is, in fact, a Hormone — not a Vitamin, and ... ..more
Urine excretion/detox of metals for prolonged periods
Supports for Kidney Health:
Kidney Support Formula RNA
CBS/NOS Compounded Supplement
#Cranberry Caps (In UltiFend and NaturoMycin Spray & Caps)
#Cranberry Juice -Sweeten with Xylitol or Super Stevia
Curbita Bladder Caps (In NaturoMycin Caps)
#SAM-e (Low dose in Ultimate B, ACAT/BHMT, MethylMax, MethylMate A, and UltiFend)
#ATP -20 (In MitoForce and MTR/MTRR/SUOX)
ME/CFS patients are notoriously very sensitive to medicines and supplements. It’s common to have adverse reactions, or to only be able to tolerate small doses.
Newbies are especially prone to taking too large of doses or going too fast. The following explains how to manage such sensitivity.
Start Low and Go Slow
Whenever you start a new medicine or supplement, it is suggested to practice Start Low and Go Slow.
This means starting with very small doses, much less than a normal dose, such as 1/8 of pill. That way, if you're going ... ..more
What does it mean to "spare dopamine"? As mentioned in the above COMT discussion. Not use it? Not create it? ..more
Andy Cutler informs us that many mercury toxic people are intolerant to certain #foods , commonly known as ‘sulfur foods’, which have a high free thiol content. Consuming foods high in thiols raises the circulating thiol levels that in turn mobilizes #mercury and creates symptoms. He notes, “You typically get a couple of hours of feeling good, energized, happy, and then libidinous, then you feel tired, draggy and depressed, which goes on for a day to a week. Of course if you are eating sulfur foods at each meal these all get stacked up and you can never figure out what ... ..more
MTHFR C677T Mutation: Basic Protocol by Dr Lynch on February 24, 2012 in C677T MTHFR Mutations
Have one or two copies of the MTHFR C677T mutation? Don’t know what to do?
After working with 100′s of individuals with this defect, I’ve developed a protocol which may help a significant number of people.
I want to make it absolutely clear that while the MTHFR C677T mutation may be common across a number of individuals, the outcome of supplementing with various nutrients can vary tremendously due to other genetic defects, dietary and lifestyle choices and environmental exposures.
Some of ... ..more
Taking #Magnesium will help to block an otherwise over-active NMDA Receptors and… calm the brain.
HOMOCYSTEINE can occupy the #Glutamate Receptor on the NMDA Receptor and over stimulate the receptive dentritic neuron and can lead to neuronal damage or “burn out” [death].
Taking MAGNESIUM is calming because in part it blocks the NMDA Receptor and buffets the excessive stimulation by TOO MUCH HOMOCYSTEINE occupying the Glutamate Receptor site.
A synapse that is gated by only NMDA is less likely to cause an excitatory post synaptic potential (EPSP) because the ion channel is blocked ... ..more