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Annonymous

What does the Livewello Gene App do?

  2 years, 7 months ago

The Raw Data you receive from 23andMe can be translated by Livewello for a 1-time fee of $19:95. LiveWello is unique because it gives users much more than just a 900 SNP Gene report: LiveWello will give you your report for 600,000 SNPs, AND attaches 11 resources for learning to each Gene.

Updates are FREE for Livewello users: Free updates are crucial as it allows users get their results for new SNPs when 23andMe adds new SNPS to your raw data during their Chip updates. It is also crucial for when new research is added to information about ... ..more

A health village is a group of people involved in your health and wellbeing. They can be family members, friends, teachers, mentors, neighbors and of course your healthcare practitioners. Once you identify them, consider creating a health village by getting a free livewello health acc at:
https://Livewello.com 
Then, add each of these people as your health village members. . With your permission, anyone who is your health village member can add/edit supplements, medications etc. This is helpful if for example, your Dr is a member of your health village.

Make sure you add other important information about your ... ..more

8 Factors that Affect Your Methylation Process

--Genetics – Like an estimated 20 percent of us, you could be genetically predisposed to high homocysteine

--Poor diet – The word “folate” comes from “foliage.” You need to eat plenty of leafy greens, beans, fruit, and whole grains to get adequate levels of vitamins B6 and B12, betaine, and folate. Egg yolks, meat, liver, and oily fish are the main dietary sources of vitamin B12 — so long-term vegan diets can be a problem. Plus, certain compounds can raise levels of homocysteine and deplete the B vitamins. These include excess animal protein, sugar, saturated fat ... ..more

SYMPTOMS OF TOO MUCH HISTAMINE
Histamine def:
“Histamine is an organic nitrogenous compound involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter. Histamine is involved in the inflammatory response.” [wiki]

FOR MORE INFORMATION:

http://headacheandmigrainen...

After eating certain histamine aggravating foods or when there is an excessive quantity of released HISTAMINE in the body symptoms may include:
Arrhythmia
Asthma
Depression
Dizziness
Dry nose
Gastrointestinal complaints
Hypotension
Itchy skin
Menstrual pain [worse]
Migraine headache
Red skin
Rhinitis [vasomotor rhinitis]
Soft stools
Tachycardia
DIAMINE OXIDASE [DAO]
Reduced function of the enzyme Diamine ... ..more

Annonymous

What does Methylation do?

  3 years, 10 months ago

The Major Tasks of Methylation
In order to provide a brief overview, the following methylation tasks have been vastly streamlined. In reality, there is an endless array of both direct and indirect Methylation activities within the human body. Even so, this summary should provide greater understanding of this highly complex pathway, as well as the complications that can arise from various defects or toxic exposures.

Methylation is responsible for the following:
1. Nervous system function (brain, spinal cord, & nerve cells). It’s critical for the insulation around nerves (myelin), which allows signals to properly transmit via this sheath, or outer ... ..more

#Parasympathetic Nervous System “Rest, repair, & digest” or “Type B’s” There are 3 basic #PNS Dominant subtypes: Basic, Extreme, & Inefficient PNS Dominant types.
The following is a summary of the average PNS Dominant type. 
 The parasympathetic nervous system (PNS) works to nourish, heal and regenerate the body. It is anabolic, which means it is concerned with rebuilding the body and storing nutrients. Its’ nerves stimulate the immune system, digestion, and urinary function. These organs include the liver, pancreas, stomach, intestines, kidneys, and bladder.

The parasympathetic nervous system, when activated by rest, relaxation and positive thinking, is essential for the elimination of wastes, emotional wellbeing and healing. When you feel absolutely stuffed and lethargic after a big Thanksgiving dinner, it is your PNS that is most active. 
 
In situations in which we have excessive parasympathetic nervous system dominance, we often find #disorganization , #depression , #apathy , and #lethargy . There may also be a decrease in clarity of thought such as “spaciness” or poor concentration. The #adrenal and #thyroid glands tend to be underactive and sex #hormones such as #estrogen , #progesterone , and #testosterone are abnormally low. There are frequently issues with multiple #allergies and sensitivities #MCS , dry skin, weight gain or a tendency toward #obesity . These are generally the people who go on the same exact “Healthy” diet as their friends or partner yet struggle to lose a few pounds. Meanwhile, everyone one else has lost 10-20 lbs and is back to their regular routine. 



Other signs and symptoms include: frequent hunger, dry/irritated eyes, unexplained sneezing or coughing, #asthma , dizziness (particularly with standing), irregular heart beats or “skipped heart beats”, low blood pressure, and #hypoglycemia as well as increased production of all digestive enzymes and bowel activity, leading to more “stomach rumbling”. #PNS Dominants rarely struggle with #constipation and may have periods of loose or frequent stools. They are also more likely to experience the feeling of being “Tired yet wired,” particularly after eating a simple carbohydrate or sugary snack.

While #SNS Dominants may also struggle with this tired yet wired sensation, it is usually more prominent in PNS Dominance. Incidentally, those who cannot tolerate higher altitudes or the more rapid drops in barometric pressure (weather changes) are more likely the PNS Dominant or “Inefficient Balanced” types as a stronger SNS is required in adjusting to higher altitudes and changing weather patterns. These are the folks who know the weather is going to change before anyone else and often suffer with allergies or headaches. They are also prone to upper #respiratory infections, which may evolve to #bronchitis or #pneumonia . Despite this, they do not tolerate hot weather as well as the other types and prefer colder climates. They are also prone to flushing and may have pinker or darker ears and a “ruddy” complexion.

Nevertheless, when these individuals are well, they can be highly creative and productive and are often slow to anger. They tend to have less interest in “left brain” academics (math or science) and often prefer “right brain” academics (art, music, & lit).

According to Dr. Gonzalez, many Nobel Prize winners in art and literature are PNS Dominants (Hemmingway, Faulkner, & Lewis). PNS Dominants typically avoid confrontational professions and enjoy those, which allow their heightened creative abilities to flourish. And, depending upon where they reside within the PNS axis, many are “foodies” who live to eat rather than simply eating to live, as SNS types tend to do. These folks typically enjoy discussing good restaurants or engaging in discussions about great meals and recipes. They typically gravitate toward meat & potatoes with some veggies usually the root (potatoes, squash, yams) or cruciferous veggies (broccoli, cauliflower, Brussel Sprouts, cabbage). In general, PNS Dominants are more sociable than SNS types. Likewise, they may prefer to remain busy yet tend to avoid exercise. Still, #genetic factors also considerably influence many of these traits.


Finally, PNS Dominants are most likely to develop immune related cancers such as malignant #melanoma , #lymphoma , #sarcoma , and #leukemia . 
 
Food priorities: It is generally helpful to evaluate the foods you crave and how you tolerate each newly introduced food. For instance, after eating meat do you feel better and more clearheaded or are you more anxious, jittery, or depressed? If you’re having a lot of digestive issues, you may want to begin with mostly cooked foods, at least to some degree, in order to reduce the strain on your digestive system. Therefore, it is important to consider whether or not you tolerate raw vs. cooked foods. Those with PNS Dominance favor butter, cream, meat, and potatoes as well as sour flavors. Yet they avoid sweets, although a heavier pastry with butter or cream is acceptable. 
 


Regrettably, many PNS Dominants have been heavily influenced by medical and nutrition experts and eat well outside their nutritional requirements. They may favor heavier, “meat & potato” meals yet eat leaner meats, whole grain carbs, fruits, and vegetables despite not feeling satisfied. While many desire bacon and egg breakfasts, they opt for the lighter fruit, toast, and yogurt fare of the SNS Dominant, thinking this is a “healthier” choice. And, even while they gag at the thought of oatmeal or cream of wheat, they do their best to find a “healthy” compromise. They frequently have a spurt of energy for 30 minutes or so, only to feel tired and lackluster within the space of an hour. Yet, if allowed to eat a thick slice of ham with potatoes, they’ll have the energy they need to work throughout the entire morning.

In fact, many “vegetarian” PNS Dominants feel much more alert and energetic when they start eating animal proteins While they sought out the heavier “allowed” proteins (cheese, eggs, hummus), most never felt satiated. 
 
For the PNS Dominant, eating meat is not “morally inferior”; it is essential for their health and survival Ultimately, each person should consume the most healthful foods for their metabolic make up. Though SNS Dominants require mostly vegetarian, raw foods, for greatest health, those who are PNS Dominant require fattier, red meats. They are hardwired to function well on the wholesome, omega 3 fats & #glutamate found in grass fed meats. Besides, most will develop a multitude of health problems if they adopt the SNS Dominant’s diet. 
 
For those with concerns regarding #sulfur , while foods such as #broccoli & #cauliflower contain a fair amount of sulfur ... ..more

STEP ONE: Layering in The Foundation
Knowing your Nervous system #dominance is an integral part in establishing the treatment process.
A). Remove or limit triggers:
Processed foods contain excitotoxins, dyes, and #toxic preservatives. It is also crucial to remove obvious food #allergies . Please see Resqua pages on #excitotoxins for more information. This is simply defined and discussed in detail. 



B). Begin general support:
Provide a good foundation for your nervous system type and begin nutritional support. Though life threatening reactions would be extremely rare (and to my knowledge, unheard of), moving too quickly can result in more intense symptoms of ... ..more

Annonymous

What does the COMT Gene Mutation mean?

  3 years, 10 months ago

What does it mean to "spare dopamine"? As mentioned in the above COMT discussion. Not use it? Not create it?  ..more

Leaky Gut Syndrome affects millions of people worldwide. While some people show antibodies in their blood indicating an immune system response to the presence of various foods, others merely show signs and symptoms of sensitivity and intolerance. Both of these conditions, and many more, are indicators of leaky gut syndrome.

WHAT IS LEAKY GUT?
Leaky gut syndrome is an un-fancy name given to increased or excessive intestinal permeability. Essentially, the walls of our digestive tracts are compromised - more porous than is healthy and normal, and as a result, particles of food, toxins, bacteria and viruses all “leak” into the bloodstream ... ..more

Annonymous

How does Methylation influence mood ?

  3 years, 9 months ago


It is important to understand the basics of methylation, and although a more detailed study of #methylation chemistry may be interesting, for our needs, it is not really necessary to study it here as it will only serve to confuse matters, so only the most important aspects will be considered.

Put simply, the methylation process makes #neurotransmitters (mood building blocks), and the issue of a person being an under or over methylator can be confusing, because there is contradiction between the various sources of information on the methylation process. For our purposes, we'll say that an over methylator is ... ..more

#Autonomic #Nervous System Dominance
The autonomic nervous system controls all of the bodily functions that are essential for survival, yet are mostly spontaneous or automatic. Your heart rate, blood pressure, digestion, and hormone production are all under the preprogrammed function of the autonomic nervous system. This critical neurological system is divided into the #parasympathetic and #sympathetic nervous systems. Aside from #genetic and biochemical factors, this division appears to be significant, influencing human conditions such as #depression , #anxiety , #cancer, #heart disease, #allergies , #ADD / #ADHD , #CFS and multiple chemical sensitivity, to name merely a few.


Leading researchers and practitioners have found that ... ..more

The #MTHFR mutations can affect the proper function of the immune system, and allergies are a result of immune system dysfunction.

There are many ways that the Methyltetrahydrofolate Reductase [MTHFR] enzyme can weaken the immune system, but I do know that if we do not have enough #SAMe then we cannot deactivate Histamine via the #Histamine N-MethylTransferase [ #HNMT ] enzyme.
If Histamine cannot be inactivated then the symptoms of excess HISTAMINE will be perpetuated.
You can find your Histamine Gene status on your #23andMe Gene Test ..more

Annonymous

What is Adrenal Fatigue ?

  3 years, 10 months ago

"Adrenal Fatigue" is a term that you hear a lot in the health community, but what is it exactly? In this article you'll learn the causes of adrenal fatigue, how it can impact how you feel, and what you can do about it!

Your adrenal glands sit on top of your kidneys and regulate many critical hormonal jobs in your body. One of those jobs is the secretion of your body's main stress hormone, cortisol. Our bodies have been designed for stressful events, and throughout time they have adapted to them. If our ancestors were chased by a ... ..more

#Autonomic #Nervous System Dominance
The autonomic nervous system controls all of the bodily functions that are essential for survival, yet are mostly spontaneous or automatic. Your heart rate, blood pressure, digestion, and hormone production are all under the preprogrammed function of the autonomic nervous system. This critical neurological system is divided into the #parasympathetic and #sympathetic nervous systems. Aside from #genetic and biochemical factors, this division appears to be significant, influencing human conditions such as #depression , #anxiety , #cancer, #heart disease, #allergies , #ADD / #ADHD , #CFS and multiple chemical sensitivity, to name merely a few.


Leading researchers and practitioners have found that ... ..more

Annonymous

What is Histamine ?

  3 years, 10 months ago

#Histamine is most commonly known for it's role in #allergic reactions but it is also involved in other neurological functions and can affect your #emotions as well as behavior. Histamine helps control the #sleep -wake cycle and promotes the release of epinephrine and #norepinephrine . This may be the explanation for red ears and #flushed cheeks in susceptible children and adults with high histamine levels.
High levels have been linked to obsessive-compulsive ( #OCD ) tendencies, #depression , and #headaches . Low levels can contribute to #paranoia , low #libido , #fatigue , and multiple medication sensitivities.
it is important to consider that those with the #CBS ... ..more

Annonymous

What does the COMT Gene Mutation mean?

  3 years, 10 months ago

To learn more about COMT Gene:
Dr. Richard Deth PhD
http://wn.com/oxidative_str...

Dr. Jill James PhD
1) http://www.ucdmc.ucdavis.ed... (2006 lectures, please scroll down for oxidative Stress Lecture as well).

2) http://www.ucdmc.ucdavis.ed... (2010 Lecture Methylation/Oxidative stress). http://www.youtube.com/watc...
 ..more

Acetylcholine is known as the inhibitory #Neurotransmitter System
The first #neurotransmitter to be discovered in 1921. Its’ importance lies in the fact that it stimulates muscles to contract. This NT alters heart muscle contractions and impacts muscle function throughout the body. It’s also strategic in vocalizations/ #speech and #swallowing . Acetylcholine is critical for #attention , #alertness , and #memory . People with #Alzheimer’s , #Parkinson’s , #ALS , and #Myasthenia Gravis have substantial #dysfunction within acetylcholine activity or breakdown.

Low levels are associated with #depression , and a lack of #concentration & #emotion as well as poor #muscle tone, #forgetfulness , and poor #sleep “light sleepers ... ..more

Annonymous

How does HISTAMINE affect you?

  3 years, 9 months ago

#HISTAMINE RECEPTORS
http://healthypixels.com/wp...

Most of us know histamines through #antihistamine drugs that relieve our suffering from #allergies to pollen, insect bites, and even foods.
Histamine is naturally produced in our body by #mastcells or white blood cells.
Histamine performs different functions by binding with histamine receptors. Depending upon their location, histamine receptors control very different body functions:

Histamine #H1 receptors:
Smooth muscle and endothelial cells affecting skin; blood vessels (Benadryl and Claritin block activity of these receptors)

Histamine #H2 receptors:
Cells in the intestines control acid secretion, abdominal pain, and nausea; heart rate
(Histamine H2 receptor antagonist ... ..more

Image


As far as I know the MTHFR mutations can affect the proper function of the immune system, and allergies are a result of immune system dysfunction.

PICTURE: Allergic orbital edema and conjunctivitis

From Dr. Carol Savage
I do not know all the ways that the Methyltetrahydrofolate Reductase [MTHFR] enzyme can weaken the immune system, but I do know that if we do not have enough SAMe then we cannot deactivate Histamine via the Histamine N-MethylTransferase [HNMT] enzyme.

If Histamine cannot be inactivated then the symptoms of excess HISTAMINE will be perpetuated.
#Homozygous #MTHFR #Heterozygous #health #Livewello #23andMe #SNPs #Genes #Methylation ... ..more

http://balancedconcepts.net...
Details of Liver Functions
The liver has a number of important functions, some of the main ones being:

Detoxification of potentially toxic chemicals from both inside and outside of the body including
drugs, alcohol and toxins from intestinal microbes. Accomplished with antioxidant nutrients
and enzymes such as glutathione. The liver detoxifies these harmful substances by a complex series of chemical reactions. The role of these various enzyme activities in the liver is to convert fat soluble toxins into water soluble substances that can be excreted in the
urine or the bile depending on the particular characteristics of ... ..more