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Physicians don't always know what to do with your genetic information because epigenetics and pharmacogenomics are relatively new fields, and everyone is trying to catch up.  Also Traditional/Allopathic physicians have very limited time in which to  go over all the information that you hand over to them, so the best way to present them with new information like this, is to share a link to your Report and make sure you tell them to read the associated medical references that come with your App. For instance, every Gene in the LiveWello Gene App report is directly linked to ... ..more

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Annonymous

What is Epinephrine

  4 years, 3 months ago

#Epinephrine is one of the “Fight or Flight” #Hormones This NT is derived from #norepinephrine & released by the #adrenals. Hence, it is also known as #adrenaline . Epinephrine is also essential in #metabolism and regulates attention and mental focus & clarity as well as arousal (alertness & waking up), and thinking. It also inhibits #insulin release and raises the amount of fatty acids in the blood; both of which you’ll require for fuel. This very neurotransmitter induced anxiety and heart racing the moment you heard the word “ #Methyltetrahydrofolate ” or “ #methylation .” Epinephrine also raises your #bloodpressure and speeds up your heart rate.
High levels have been linked to sleep problems, #anxiety and #ADD or #ADHD. Low levels can result in #fatigue , lack of focus, and difficulty losing weight. ..more

High dose #FolicAcid is the worst thing a person with the MTHFR gene mutation should take.
If a doctor tells a person with the #MTHFR gene mutations to take Folic ACID then that doctor does not really understand anything about the #L-Methyl Folate receptors on the Blood Brain Barrier [BBB]. The doctor does not realize that high dose Folic ACID is just going to block up the L-Methyl Folate Receptors on the BBB. When Folic ACID gets into the L-Methyl Folate Receptors it BLOCKS the receptor and it doesn't get into the brain and neither does the L-Methyl ... ..more

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There is little known about the A1298C MTHFR mutation. Or so it seems.
Research seems to ignore it almost completely while the C677T MTHFR mutation gets all the attention and glory.
For those who have the A1298C MTHFR mutation, this is frustrating.
Symptoms exist and doctors are saying there is no correlation between the MTHFR A1298C mutation and your symptoms – right?

I’d like to prove them wrong – at least for the symptoms which do correlate with the A1298C MTHFR mutation.

The MTHFR A1298C mutation may affect you if you are either:
--Homozygous A1298C MTHFR mutation
--Compound heterozgous A1298C + C677T ... ..more

Annonymous

What are Neurotransmitters

  4 years, 3 months ago

Perhaps the best way to think of neurotransmitters is with an automobile example. Most automobiles in the United States are made to cruise at 60-70 miles per hour, perfect for interstate highways and that summer vacation. If we place that same automobile on a racetrack and drive day-after-day at 130 mph, two things would happen:
1). Parts would fail and
2). We would run the engine so hot that we’d likely evaporate or burnout the oil.
In fact, neurotransmitters such as serotonin act as the brain’s “oil”.

Comparable to a normal automobile on a race track, when we ... ..more

Annonymous

What is an Excitotoxin ?

  4 years, 3 months ago

#Excitotoxins excite the nerve or brain cell to death.

MSG/Glutamates Please do not attempt to eliminate every last version of #MSG from your diet or you’ll be absolutely insane by the end of the month, it is much too difficult. Just be mindful that there are a lot of hidden ingredients everywhere If a restaurant says they have no MSG in their food, they are almost always referring to the fact that they don’t add MSG to their food but it comes in vats that way already. Also, there are loopholes so that food manufacturers may label ... ..more

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A chemical made in the BH4 cycle, which is used to produce dopamine and serotonin, neurotransmitters strategic in regulating mood, sleep, attention and focus, reward seeking behavior, addiction, and sense of wellbeing. BH4 is also critical in the urea cycle (waste facility) for cleaning up ammonia and making nitric oxide. A shortage of this important chemical has widespread repercussions.

Tetrahydrobiopterin BH4 Cycle produces the BH4 used for making neuro-talkers (dopamine, epinephrine, nor-epi, serotonin, & melatonin). It cleans up toxic ammonia in The Waste Cycle & makes Nitric oxide to protect the heart & brain.

Though controversy exists regarding this cycle’s function, Dr. Yasko’s theory indicates that The Big Motherflipper (MTHFR A1298C) may drive this cycle in the reverse direction and several independent studies support this finding. This leads to a chemical exchange among BH2 to BH4, a multi-purpose product that is used in both the Waste Facility (urea cycle) and BH4 Industry. Within the Better Health 4 Life Industry, BH4 produces chemicals known as neurotransmitters, or neurotalkers (NTs), including dopamine, serotonin, melatonin, norepinephrine, and epinephrine. NTs are central for the communication between nerves and cells as well as stabilizing the crisis response, mood, and sleep cycles. Chronically low BH4 levels increase the risk for ADD/ADHD, Bipolar Disorder, OCD, insomnia, depression, anxiety, and many other quality of life issues. Think of this company as AT&T with a philanthropic twist since it donates BH4 to the Waste Facility for environmental clean up as well as supporting the community in health & wellbeing.

The Waste Facility uses BH4 to clean up toxic ammonia and generates nitric oxide, an element that keeps blood vessels open and free of plaque. Yet if BH4 is scarce, it cannot clean up waste or deliver vital nutrients to the Power Plant (fumarate) so that noxious chemicals back up into SAM’s Corporation. Given the fact that it takes 2 grains of BH4 to clean up 1 granule of ammonia, as well as 2 of BH4 to create just 1 bit of nitric oxide, its easy to see how problems might arise. This underscores the BH4 Industry’s role throughout the community since unlike an actual factory; it isn’t permitted to shut down for repairs or maintenance.

While there are many factors that may impact this cycle, several are listed below:

1. A ... ..more

Annonymous

What is Dopamine ?

  4 years, 3 months ago

Think “delightful dialogue” with #dopamine since this #neurotransmitter is crucial for happiness, a sense of wellbeing, and language. It’s also involved in #muscle control and function. Dopamine is responsible for #motivation , interest, #mood , #speech , and contentment. It is also associated with positive #stress states such as being in love, exercising, listening to music, and of course, #sex . When you don't have enough dopamine, you may have difficulty initiating or completing tasks. Deficiencies also lead to poor #concentration , little or no energy, and lack of motivation. This could be the culprit if you lack the initiative to study the ... ..more

There are around 100,000 synthetic chemicals available on the market today, in everything from shampoo to cleaning products, toys to baby bottles, furniture, carpet and even clothes.

But did you know that most of them have not been tested for human and environmental toxicity? Of those that have been, they contain many known and suspected carcinogens, allergens and endocrine disrupters—even in products you put on your skin.

In fact, one in three personal care products contains ingredients identified as possible human carcinogens, approximately one in five contains ingredients commonly contaminated with known carcinogens, and almost one in two ... ..more

Annonymous

WHO KNOWS ABOUT MTHFR ?

  4 years, 4 months ago

The two groups of doctors who are the most likely to know something about the Methyltetrhydrofolate Reductase [MTHFR] enzymatic gene mutation[s] are the OB/GYNs and the Psychiatrists. I would think more Cardiologists would be on top of this topic because of the associated elevated HOMOCYSTEINE levels but they are starting to pay attention. The Geneticists aren't very interested in MTHFR because it isn't lethal or seriously dangerous in and of or by itself.

#Homozygous #MTHFR #Heterozygous #health #Livewello #23andMe #SNPs #Genes #Methylation
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Acetylcholine is known as the inhibitory #Neurotransmitter System
The first #neurotransmitter to be discovered in 1921. Its’ importance lies in the fact that it stimulates muscles to contract. This NT alters heart muscle contractions and impacts muscle function throughout the body. It’s also strategic in vocalizations/ #speech and #swallowing . Acetylcholine is critical for #attention , #alertness , and #memory . People with #Alzheimer’s , #Parkinson’s , #ALS , and #Myasthenia Gravis have substantial #dysfunction within acetylcholine activity or breakdown.

Low levels are associated with #depression , and a lack of #concentration & #emotion as well as poor #muscle tone, #forgetfulness , and poor #sleep “light sleepers ... ..more

Annonymous

Any thoughts on MTHFR and Lithium ?

  4 years, 3 months ago

#MTHFR #Lithium
Lithium has been known for years to be useful for #bipolar disorder. Despite all that is known about lithium and its impact on biochemical pathways, no one has defined the mechanism by which lithium has its impact on bipolar disorder. It is likely to be an effect on multiple pathways. There are a number of enzymes in the body that are known to be impacted and inhibited by lithium.

Lithium comes together with methylation at #COMT, the enzyme catechol-o-methyl-transferase. COMT breaks down #dopamine and #norepinephrine. Dopamine is a critical #neurotransmitter for motivation, focus and attention, among other functions ... ..more

Julie Matthews: There is overwhelming scientific support for “diet and nutrition intervention” for ADHD and autism. Many studies indicate that children with autism and ADHD have deficiencies in nutrients such as zinc, iron, fatty acids, and that supplements improved symptoms. There are studies showing benefit with nutritional support for autism and ADHD. There are also studies on B6 and magnesium helping improve symptoms of autism. One study on children with autism showed that a multivitamin-mineral formula improved all areas of autistic symptoms studied including: language, play, sociability, hyperactivity, cognition, eye contact, and more. The aggregate science screams “pay attention to ... ..more