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Annonymous

What does the COMT Gene Mutation mean?

  3 years, 4 months ago

To learn more about COMT Gene:
Dr. Richard Deth PhD
http://wn.com/oxidative_str...

Dr. Jill James PhD
1) http://www.ucdmc.ucdavis.ed... (2006 lectures, please scroll down for oxidative Stress Lecture as well).

2) http://www.ucdmc.ucdavis.ed... (2010 Lecture Methylation/Oxidative stress). http://www.youtube.com/watc...
 ..more

#23andme currently only tests for THREE mutations in these genes. So, even if 23andme says you are normal for all three mutations, you could still have a harmful mutation somewhere else in one of these genes. Any harmful mutation means a person has Hereditary Breast/ #OvarianCancer Syndrome.

The three mutations 23andme tests for are found mostly in Ashkenazi (Eastern European) Jews. It just happens that these three mutations are easy to test for and are well-studied.

As a general rule, you are hoping NOT to see DI as the genotype at any of your #BRCA1 and #BRCA2 locations. Genotype DI ... ..more

Vitamin B12 is one of the most frequently prescribed treatments in chronic fatigue syndrome (ME/CFS) yet it is not uncommon
for it to perform poorly or even to have negative effectsthus. Here Fred provides some of the reasons he believes B12 does not sometimes work in ME/CFS

Taking It in Tablet Form- Active b12 is taken as an oral tablet reducing its absorbtion to below 1%. A 1000mcg active b12 oral tablet might bind as much as 10mcg of b12. Again the b12 has to be squeezed through a keyhole that limits the amount and is subject to ... ..more

#23andme currently only tests for THREE mutations in these genes. So, even if 23andme says you are normal for all three mutations, you could still have a harmful mutation somewhere else in one of these genes. Any harmful mutation means a person has Hereditary Breast/ #OvarianCancer Syndrome.

The three mutations 23andme tests for are found mostly in Ashkenazi (Eastern European) Jews. It just happens that these three mutations are easy to test for and are well-studied.

As a general rule, you are hoping NOT to see DI as the genotype at any of your #BRCA1 and #BRCA2 locations. Genotype DI ... ..more

To upload a file from your mobile device, you will need to have already saved it to a cloud storage app, such as Google drive or Dropbox.

1. Sign into your Livewello account
2. Select the “Genetics” tab, then “Variance reports”
3. Purchase the gene app
4. Click the upload button
5. A popup will appear displaying your cloud storage options e.g. Dropbox, Google Drive
6. Select your file and upload. ..more

VDR Taq has a minor allele (MAF) of "G":
http://www.ncbi.nlm.nih.gov...

Here are some studies that reference VDR Taq (rs731236):

"We observed that women with GG (rs731236), ... were characterized by a significant correlation between vitamin D vs testosterone concentration and FAI value. We found a significant correlation between testosterone level and FAI vs vitamin D concentration in men with heterozygote AG in the rs731236 polymorphism"
http://www.ncbi.nlm.nih.gov...

"The VDR polymorphism, TaqI (rs731236), was associated with a 26 % risk reduction (TT vs. CC, OR 0.74)"
http://www.ncbi.nlm.nih.gov...

All ... ..more

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Annonymous

What does the Livewello Gene App do?

  2 years, 2 months ago

The Raw Data you receive from 23andMe can be translated by Livewello for a 1-time fee of $19:95. LiveWello is unique because it gives users much more than just a 900 SNP Gene report: LiveWello will give you your report for 600,000 SNPs, AND attaches 11 resources for learning to each Gene.

Updates are FREE for Livewello users: Free updates are crucial as it allows users get their results for new SNPs when 23andMe adds new SNPS to your raw data during their Chip updates. It is also crucial for when new research is added to information about ... ..more

1) Get a Standard Health Report. Go to https://livewello.com/snps and upload your raw data gene results file.

How does the Livewello App work with your Genetic Raw Data?
https://docs.google.com/a/l...

2) Get a Healthcare Practitioner who is qualified and understands Epigenetics.
Share your Report with your Healthcare Practitioner
Since a software application doesn't know your unique symptoms, your other functional lab levels and a host of your other important health variables, it would be unsafe for it to dispense a safe treatment plan without this information. What you'll need next is ... ..more

For most people a Variance report with only 300 SNPs doesn't paint a complete picture.As such, they will need to delve deeper into their genome to figure out what is going on. Most people do not realize that their 23andMe Raw Data comes with 600,000 Disease related SNPs. All of which have research being added to the PubMed Database almost daily. Every Gene in your Livewello Report has a live connection to up-to-date research information from PubMed, SNPedia, WikiGenes, Malacards, GHR, Medline, OMIM, dbSNP, Ensembl and Google Scholar. New information and Research is being added almost daily ... ..more

Annonymous

What is SNP Sandbox?

  2 years, 2 months ago

The Sandbox tool is for creating an unlimited number of customized Health Reports with your raw data from 23andMe AncestryDNA or most other personal genomics testing companies. You can use it to create a customized report based on any Gene or SNP name you want added to it. It works best once you upload your raw data file.

This tool allows you to add thousands of SNPs of YOUR choice to your Report. You can use it to add SNPs to your Report that are not in your Standard Variance Report. So, if you've received your 23andMe, Ancestry, FTDNA ... ..more

Now that you have your gene variance report, you should find a licensed and experienced health practitioner that will work with you and explain what your genotypes mean for your health. If you do not yet have a practitioner that is experienced in genetics, you can send a private message to one of the self-identified health practitioners in our database: https://livewello.com/pract...
(Note - These practitioners are not affiliated with Livewello, so you will need to verify their credentials on your own )

Another alternative would be to post general questions in our health community https://livewello.com/commu...
#Livewello ..more

Published by Frank Marshall · March 26, 2015 at 2:12pm

The Compare Reports Tool allows you to view and compare up to 5 different people's Gene variance reports side-by-side. Comparing your Gene Reports provides side-by-side comparison with other profiles like the friends or family members in your LiveWello Account.

This tool is for those who have received their Gene results from 23andMe AncestryDNA or almost any other Gene Testing company.

Before you can do this, please make sure that:



--Everyone has generated the same Livewello Gene report you want to compare.


--Everyone has exchanged their "Add-Me" link with each ... ..more