Introduction to The Vagus Nerve
In people with fatigue, food sensitivities, anxiety and gut problems, brain fog and depersonalization, the vagus nerve is almost always at play. These people have lower vagal tone, which means a lower ability of the vagus nerve to activate.
The only question is what aspect of the vagus nerve is malfunctioning and how much the vagus nerve is a problem vs. other aspects of your biology.
The vagus nerve is part of the parasympathetic nervous system, referred to as the rest and digest system. It’s not the only nerve ... ..more
Vitamin B12 is one of the most frequently prescribed treatments in chronic fatigue syndrome (ME/CFS) yet it is not uncommon
for it to perform poorly or even to have negative effectsthus. Here Fred provides some of the reasons he believes B12 does not sometimes work in ME/CFS
Taking It in Tablet Form- Active b12 is taken as an oral tablet reducing its absorbtion to below 1%. A 1000mcg active b12 oral tablet might bind as much as 10mcg of b12. Again the b12 has to be squeezed through a keyhole that limits the amount and is subject to ... ..more
The Raw Data you receive from 23andMe can be translated by Livewello for a 1-time fee of $19:95. LiveWello is unique because it gives users much more than just a 900 SNP Gene report: LiveWello will give you your report for 600,000 SNPs, AND attaches 11 resources for learning to each Gene.
Updates are FREE for Livewello users: Free updates are crucial as it allows users get their results for new SNPs when 23andMe adds new SNPS to your raw data during their Chip updates. It is also crucial for when new research is added to information about ... ..more
1) Get a Standard Health Report. Go to https://livewello.com/snps and upload your raw data gene results file.
How does the Livewello App work with your Genetic Raw Data?
2) Get a Healthcare Practitioner who is qualified and understands Epigenetics.
Share your Report with your Healthcare Practitioner
Since a software application doesn't know your unique symptoms, your other functional lab levels and a host of your other important health variables, it would be unsafe for it to dispense a safe treatment plan without this information. What you'll need next is ... ..more
For most people a Variance report with only 300 SNPs doesn't paint a complete picture.As such, they will need to delve deeper into their genome to figure out what is going on. Most people do not realize that their 23andMe Raw Data comes with 600,000 Disease related SNPs. All of which have research being added to the PubMed Database almost daily. Every Gene in your Livewello Report has a live connection to up-to-date research information from PubMed, SNPedia, WikiGenes, Malacards, GHR, Medline, OMIM, dbSNP, Ensembl and Google Scholar. New information and Research is being added almost daily ... ..more
This Livewello feature helps you find and generate your own results on Genes that Genome wide Research Studies have associated to certain Health Conditions based on research studies.
1) Go to: https://livewello.com/gwas and enter the name of your health condition. If research has been done on it, the SNPs/Genes and research studies associated with that health condition will pull up.
2) Once it does, click "copy to sandbox" and
3) Click build SNP Template to view your own report.
HYPOTHYROIDISM GENES: https://livewello.com/snps/...
ULCERATIVE COLITIS GENES: https://livewello.com/snps/...
The Sandbox tool is for creating an unlimited number of customized Health Reports with your raw data from 23andMe AncestryDNA or most other personal genomics testing companies. You can use it to create a customized report based on any Gene or SNP name you want added to it. It works best once you upload your raw data file.
This tool allows you to add thousands of SNPs of YOUR choice to your Report. You can use it to add SNPs to your Report that are not in your Standard Variance Report. So, if you've received your 23andMe, Ancestry, FTDNA ... ..more
Now that you have your gene variance report, you should find a licensed and experienced health practitioner that will work with you and explain what your genotypes mean for your health. If you do not yet have a practitioner that is experienced in genetics, you can send a private message to one of the self-identified health practitioners in our database: https://livewello.com/pract...
(Note - These practitioners are not affiliated with Livewello, so you will need to verify their credentials on your own )
Another alternative would be to post general questions in our health community https://livewello.com/commu...
Published by Frank Marshall · March 26, 2015 at 2:12pm
The Compare Reports Tool allows you to view and compare up to 5 different people's Gene variance reports side-by-side. Comparing your Gene Reports provides side-by-side comparison with other profiles like the friends or family members in your LiveWello Account.
This tool is for those who have received their Gene results from 23andMe AncestryDNA or almost any other Gene Testing company.
Before you can do this, please make sure that:
--Everyone has generated the same Livewello Gene report you want to compare.
--Everyone has exchanged their "Add-Me" link with each ... ..more
You probably have done your Gene Test for a variety of reasons that may not have included your health. Did you know that your Gene results contain information about mutations that research has associated with certain health issues? This information can include your potential risk for certain health conditions. Of course, we always advise that any information our software provides for you is discussed with your Doctor but it is important to maximize the information in your Gene results. Read: Methylation: Why It Matters For Your Immunity, Inflammation & More
6 Ways A DNA Test Can Help You Optimize Your Diet
Matching Genes and Vitamins. A Personalized Plan May Be in Your Future
Why would you need to run a Genetics test?
LiveWello is unique because it gives you much more than just a Gene report: The Livewello Gene App will give you Gene reports for 600,000 SNPs and conveniently attaches 12 resources for learning to each Gene. The App also offers free updates that reflect your results when 23andMe adds more SNPs to your raw data. The reason for this feature, is that we believe that people should have information for all the Genes in their Raw Data not just some of them. That way, you and your Heallthcare Practitioner can have the benefit of all this information when creating your treatment plan. Basically, as long as a SNP is in your Raw Data with rsID and Minor Allele, the App will generate your Gene Report for it.
So, how does the Livewello App work ?
1) Download your Raw Data from 23andMe, Ancestry.com or FTDNA etc. Save it to your desktop.
2) Go to the home page at: https://livewello.com/genetics
On that page, you can learn more about our genetics tools. Then, click the "Get Started" button to upload your raw data and pay the 1-time fee of 19:95. The raw data file you upload into the App should not be altered in any way. i.e. Do not edit the file name, file format or contents.
3) Livewello currently gives you unlimited Health reports for about 600,000 SNPs in your Raw Data. Once you’re done with uploading your raw data, you can start generating your Health Reports with these free tools:
a) The Gene Library is searchable and has thousands of FREE Health Reports you will find helpful and can download: https://livewello.com/snps/...
It is designed to give your health reports on Genes that Research Studies have associated with your health issues and Diagnosis. Share your reports with your Doctor. These Gene Reports could be good indicators that your Doctor may need to order further lab/diagnostic testing. As a Livewello Gene App user, you can install as many Gene Reports as you'd like. There is no limit!
b) The GWAS Health Conditions Tool
If you don’t see Gene Reports about your health issues in the Gene Library, use this tool:
It will give you health reports on Genes that Research Studies have associated with your health issues and Diagnosis: https://livewello.com/gwas
DIRECTIONS FOR THE GWAS Health Conditions FEATURE
To use the GWAS Health Conditions Tool go to https://livewello.com/gwas
i. Simply enter the health condition's name to see if any Genome-wide studies have been done on that condition. If studies exist, as you type, results will come up. Click on the result that matches your search.
ii. Click on "copy to SNP sandbox" and
iii. Click "build template" and "view report" to generate a report for yourself.
c) The SNP Sandbox Tool Use it to create customized Gene Reports based on any Gene or SNP names you choose to have in it. How-To Video: http://vimeo.com/103512972
EXAMPLES: YASKO'S NUTRIGENOMIC SNPs: https://livewello.com/snps/...
MTHFR Gene SNPs ... ..more
You have been diagnosed with a chronic health condition. Your genetic information will help you determine which genes or biochemical pathways were altered to result in that health condition. Getting to the root cause, will help facilitate recovery by tailoring any treatment plans and lifestyle changes your Doctor recommends specifically to your body.
Several members of your family live with one or several chronic health issues. Genetic information will help your family uncover the inherited Gene sequence patterns that contribute to the chronic illnesses plaguing them.
You plan to have a baby: Research is implicating certain genetic mutations in a ... ..more
A Standard Gene Report with information looks like this: https://livewello.com/snps/... This sample contains some useful info worth sharing with your Doctor.
1) When your Gene report is created, click the Gene itself (or the "i" icon in a Template). Livewello will link 12 Learning Resources directly to each of the Genes in your report. They are: Medline, GHR, Google Scholar, dbSNP, Ensembl, Wiki Genes, SNPedia Wiki Genes, Malacards and PubMed. If the info is not readily available, re-enter your gene name or health condition into that resource's search box to check if any further information is ... ..more
COMT and VDR Genes and DOPAMINE and NOREPINEPHERINE…and people sensitive to methyl donors.
Those with the Vitamin D Receptor Taq [VDR Taq (+/+)] mutations do not make Dopamine and therefore Norepinepherine very well.
Those with the Catechol-O-Methyl Transferase [COMT +/+] mutations cannot break down Dopamine and Norepinephrine very well.
A normal VDR [-/-] and the abnormal COMT [+/+] enzyme essentially aggravate the situation so that the concentration of Dopamine may be increased.
When the person has a perfect VDR taq [-/-] and they have the COMT [+/+] mutations then:
The good working VDR taq [-/-] allows them to make plenty of Dopamine.
The lousy COMT [+/+] causes ... ..more
By Carol Savage
"Is it possible for people to be low in L-Methyl Folate [5-MTHF] even if they do NOT have single nucleotide polymorphisms affecting the MTHFR enzyme?"
The answer is... YES.
A person can have terrible nutrition. Someone who doesn't eat anything green. Someone who never eats beans. A poor diet low in DiHydroFolate [DHF] can cause there to be insufficient L-Methyl Folate.
This includes thousands of people on coumadin [warfarin] who avoid eating greens and people with Rheumatoid Arthritis [RA] who have been given Methotrexate. Methotrexate blocks the enzyme that converts DHF into TetraHydroFoalte [THF ... ..more