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Adverse reactions to fluoroquinolone #antibiotics ( #Cipro #Ciprofloxacin #Levaquin #Levofloxacin #Avelox #Moxifloxacin and #Floxin #Ofloxacin ) can manifest in patients as a multi-symptom chronic illness that most resembles #fibromyalgia #chronic fatigue syndrome #CFS / #myalgic encephalopathy (ME) and/or an #autoimmune diseases. As is the case with those chronic multi-symptom illnesses, the symptoms of fluoroquinolone toxicity vary greatly from one individual to another. Though almost everyone who suffers from fluoroquinolone toxicity has some sort of musculoskeletal issues (fluoroquinolones have a black box warning about the risk of tendon rupture), #neuropathy and autonomic nervous system dysfunction, those broad categories of symptoms are where the ... ..more

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#bloodsugar #diabetes diet #glaucoma #glucose #insulin #vitaminc
Diabetes and Glaucoma: A New Perspective

A study at the University of Michigan found people with diabetes have a 35% higher chance of having Glaucoma than people who do not. The study went on to say the reason for the higher rates of glaucoma in diabetics is “unknown.” My purpose for writing this article is to explain the nutritional reasons that diabetes and glaucoma often go hand in hand.

Before going further, let me state this very clearly: The purpose of this article is to provide education. Both diabetes and glaucoma are serious ... ..more

Annonymous

What does the COMT Gene Mutation mean?

  4 years, 2 months ago

What does it mean to "spare dopamine"? As mentioned in the above COMT discussion. Not use it? Not create it?  ..more

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Annonymous

What are Free Radicals & Oxidants ?

  4 years, 2 months ago

We frequently hear terms such as free radicals, #oxidative stress, and #antioxidants yet what exactly do these mean? Normally, a healthy cell has paired electrons—one that is positive and another that is negative.

Free radicals are molecules without positive electrons and are created whenever there is oxidation, AKA oxidative stress. This is really just a normal part of the everyday fallout of metabolism and by itself, isn’t necessarily a bad thing. Nonetheless, a city overwrought by criminals easily overwhelms the honest and industrious residents. Soon enough, the best and brightest citizens flee to the suburbs while this once ... ..more

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Annonymous

What does the COMT Gene Mutation mean?

  4 years, 2 months ago

To learn more about COMT Gene:
Dr. Richard Deth PhD
http://wn.com/oxidative_str...

Dr. Jill James PhD
1) http://www.ucdmc.ucdavis.ed... (2006 lectures, please scroll down for oxidative Stress Lecture as well).

2) http://www.ucdmc.ucdavis.ed... (2010 Lecture Methylation/Oxidative stress). http://www.youtube.com/watc...
 ..more

Annonymous

Any thoughts on MTHFR and Lithium ?

  4 years, 2 months ago

#MTHFR #Lithium
Lithium has been known for years to be useful for #bipolar disorder. Despite all that is known about lithium and its impact on biochemical pathways, no one has defined the mechanism by which lithium has its impact on bipolar disorder. It is likely to be an effect on multiple pathways. There are a number of enzymes in the body that are known to be impacted and inhibited by lithium.

Lithium comes together with methylation at #COMT, the enzyme catechol-o-methyl-transferase. COMT breaks down #dopamine and #norepinephrine. Dopamine is a critical #neurotransmitter for motivation, focus and attention, among other functions ... ..more

Annonymous

What does the COMT Gene Mutation mean?

  4 years, 2 months ago

To learn more about COMT Gene:
Dr. Richard Deth PhD
http://wn.com/oxidative_str...

Dr. Jill James PhD
1) http://www.ucdmc.ucdavis.ed... (2006 lectures, please scroll down for oxidative Stress Lecture as well).

2) http://www.ucdmc.ucdavis.ed... (2010 Lecture Methylation/Oxidative stress). http://www.youtube.com/watc...
 ..more

1) Biopterin/Neopterin: For those with A1298C mutations, #BH4 (also known as tetrahydrobiopterin) levels are typically quite low. This test provides insight to how low these levels are and why. If neopterin levels are high, then I am considering the possibility of a lingering infection, inflammation or chronic immune response that is preventing #biopterin from being formed. Thus, this test provides information not only potentially low biopterin levels but also why they may be low.

If a doctor simply prescribes BH4 without understanding the need to address the inflammation and chronic infections, it is band-aide treatment over a gaping wound ... ..more

MAO A Monamine Oxidase. This “Mops up Serotonin”
This enzyme defect allows you to spare serotonin, another “feel good hormone”. A partial defect can be useful in maintaining this important neuro-talker in the community, particularly when bacteria are present. Bacteria often gobble up tryptophan, the major precursor to serotonin so that anyone with bacterial issues (history of recurrent infections, gut issues, etc), tend to have low serotonin levels. Nevertheless, a full defect can lead to more serotonin sparing, though you are probably still somewhat low despite this full block.

Since this enzyme acts much like the COMT, only in filtering ... ..more

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