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Annonymous

How can I stimulate my vagus nerve

  2 years, 8 months ago

SOURCE: http://selfhacked.com/2015/...


Introduction to The Vagus Nerve

In people with fatigue, food sensitivities, anxiety and gut problems, brain fog and depersonalization, the vagus nerve is almost always at play. These people have lower vagal tone, which means a lower ability of the vagus nerve to activate.

The only question is what aspect of the vagus nerve is malfunctioning and how much the vagus nerve is a problem vs. other aspects of your biology.

The vagus nerve is part of the parasympathetic nervous system, referred to as the rest and digest system. It’s not the only nerve ... ..more

The MTHFR gene provides instructions for making an enzyme called methylenetetrahydrofolate reductase. This enzyme plays a role in processing amino acids, the building blocks of proteins. Methylenetetrahydrofolate reductase is important for a chemical reaction involving forms of the B-vitamin folate (also called folic acid or vitamin B9). Specifically, this enzyme converts 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate. This reaction is required for the multistep process that converts the amino acid homocysteine to another amino acid, methionine. The body uses methionine to make proteins and other important compounds.
How are changes in the MTHFR gene related to health conditions?
homocystinuria - caused by mutations ... ..more

Methylation is a key biochemical process that is essential for the proper function of almost all of your body’s systems. It occurs billions of times every second; it helps repair your DNA on a daily basis; it controls homocysteine (an unhealthy compound that can damage blood vessels); it helps recycle molecules needed for detoxification; and it helps maintain mood and keep inflammation in check.

To keep methylation running smoothly you need optimal levels of B vitamins. Without enough B vitamins methylation breaks down, and the results can be catastrophic. In these cases we see more birth defects like spina ... ..more

Annonymous

What is Methylation?

  4 years ago

Methylation
The methylation pathway can be likened to the body’s chief housekeeping and maintenance systems. It is responsible for many of the most complex and vital undertakings throughout the body, occurring each time the body takes one substance and turns it into another. This chemical exchange occurs between enzymes, amino acids, proteins, and other molecules in order to maintain cell function. Methylation regulates gene expression, allowing beneficial genes to function while keeping less desirable genes at bay. It also provides the backbone for the immune system, DNA, RNA, cellular repair, detoxification, hormone regulation, and communication between the cells and ... ..more

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From: http://www.stopthethyroidma...
"As explained well in the revised STTM book, which you should have on hand and bookmarked at the doctors office. The book is in English, Spanish, German and Swedish.

TSH: for diagnosis of hypopituitary, NOT to diagnose or dose your hypothyroidism (unless it’s high). If you allow a doctor to diagnose or dose you by this lab test and range i.e. to say you are normal simply because it’s in range or below 10…you’ll could still be hypothyroid.
Free #T4 and Free #T3 (note the word “free”–important since it measures ... ..more


It produces a defective MTHFR enzyme of different varieties i.e. it functions less than optimally, such as performing at only 40% of its capacity, or 70% of its capacity. It can mean you won’t break down toxins or heavy metals well i.e. you could find yourself with high iron, or high copper, or high mercury….etc. High copper can also cause low iron.
The defective enzyme doesn’t break down folate vitamins properly (of which folic acid is the precursor to), which can cause high homocysteine, which can increase your risk of coronary heart disease (arteriosclerotic vascular ... ..more

Methylenetetrahydrofolate reductase (MTHFR) supports one's health, well-being and detoxification and can be defective in a fairly large percentage of our population. About 45% of Caucasians, 70% of Hispanics and about 30% of southern Italians have a genetic defect.

The MTHFR gene produces the MTHFR enzyme. This enzyme is responsible for the circulating form of folate. Folate is very important in homocysteine regulation. The MTHFR enzyme metabolizes folic acid into 5-MTHF, which is needed to combine with homocysteine to break it down and to facilitate methylation (detoxification) processes in the body. The MTHFR enzyme is essential for the body to ... ..more

Annonymous

How does Methylation influence mood ?

  4 years, 3 months ago


It is important to understand the basics of methylation, and although a more detailed study of #methylation chemistry may be interesting, for our needs, it is not really necessary to study it here as it will only serve to confuse matters, so only the most important aspects will be considered.

Put simply, the methylation process makes #neurotransmitters (mood building blocks), and the issue of a person being an under or over methylator can be confusing, because there is contradiction between the various sources of information on the methylation process. For our purposes, we'll say that an over methylator is ... ..more

#Autonomic #Nervous System Dominance
The autonomic nervous system controls all of the bodily functions that are essential for survival, yet are mostly spontaneous or automatic. Your heart rate, blood pressure, digestion, and hormone production are all under the preprogrammed function of the autonomic nervous system. This critical neurological system is divided into the #parasympathetic and #sympathetic nervous systems. Aside from #genetic and biochemical factors, this division appears to be significant, influencing human conditions such as #depression , #anxiety , #cancer, #heart disease, #allergies , #ADD / #ADHD , #CFS and multiple chemical sensitivity, to name merely a few.


Leading researchers and practitioners have found that ... ..more

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#Autonomic #Nervous System Dominance
The autonomic nervous system controls all of the bodily functions that are essential for survival, yet are mostly spontaneous or automatic. Your heart rate, blood pressure, digestion, and hormone production are all under the preprogrammed function of the autonomic nervous system. This critical neurological system is divided into the #parasympathetic and #sympathetic nervous systems. Aside from #genetic and biochemical factors, this division appears to be significant, influencing human conditions such as #depression , #anxiety , #cancer, #heart disease, #allergies , #ADD / #ADHD , #CFS and multiple chemical sensitivity, to name merely a few.


Leading researchers and practitioners have found that ... ..more

Besides the most obvious reason to take Oral Contraceptives/BCPs, you can also be prescribed them for medical reasons. It could be endometriosis, estrogen dominance or others. However taking BCPs when you have the MTHFR mutation may cause some problems. This would also be true if you already had pernicious anemia.

Taking the Pill effects Folate and B12 metabolism. Since having the MTHFR mutation already effects these two items taking BCPs just weakens the folate cycle further. I believe folks without the mutation can just up the amount of food they take with folate in it. But if you have ... ..more

Annonymous

What is Homocysteine ?

  4 years, 3 months ago

#Homocysteine is a toxic waste by-product of protein and amino acid metabolism, and #methylation in the body is going on constantly, converting this damaging homocysteine into the #antioxidant #glutathione.
Methylation also converts homocysteine into an important biochemical called #SAMe , a vital methyl donor for the production of the all important neurotransmitters dopamine, serotonin and their derivatives. This is how the body makes good use of this toxic element.

Keeping homocysteine at a healthy, low level is extremely important for keeping our risk of heart disease, stroke and Alzheimer's disease as low as possible. High levels of homocysteine, if left ... ..more